2007
DOI: 10.1136/thx.2006.072256
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Survival of HIV-infected patients in the intensive care unit in the era of highly active antiretroviral therapy

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Cited by 108 publications
(137 citation statements)
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“…However, specific HIV characteristics (CD4 cell count, plasma HIV-RNA load, HIV-related diagnosis, or antiretroviral therapy) have not been clearly identified as predictors of ICU mortality [4,15,37,38,[49][50][51][52][54][55][56][57][58][59], although some reports have associated CD4…”
Section: Discussionmentioning
confidence: 99%
“…However, specific HIV characteristics (CD4 cell count, plasma HIV-RNA load, HIV-related diagnosis, or antiretroviral therapy) have not been clearly identified as predictors of ICU mortality [4,15,37,38,[49][50][51][52][54][55][56][57][58][59], although some reports have associated CD4…”
Section: Discussionmentioning
confidence: 99%
“…On the other hand, a retrospective study by Dickson et al did not show a better outcome in patients receiving ART (although in this study no patient began ART at admission) [20]. Similarly, a prospective study conducted by Japiassu et al showed that ART use did not affect hospital survival, leaving the mortality rate at 50% both in those who received ART and those who did not [5].…”
Section: Continue Stop or Introduce Art In A Hiv-positive Patient Wimentioning
confidence: 78%
“…The introduction of antiretroviral therapy has led to substantial changes in the epidemiology of IPD in HIV-positive patients over the last decades [6]. Studies on this subject have shown a decreasing incidence of BPI as an indirect consequence of the implementation of HAART therapy, most likely due to the drug-generated immune reconstruction [5,7]. In USA, even with an effective therapeutic control of HIV infection, the risk of developing IPD was 35 times higher than in seronegative individuals [6].…”
Section: Discussionmentioning
confidence: 99%
“…However, there is a cumulative risk factor involved in the determinism of severe infections in HIV-infected patients: race, ethnicity, training, drug and/or alcohol use, smoking, co-morbidities, repeated hospitalizations, co-infection with hepatitis viruses, low levels of CD4 T lymphocytes, high viremia, adherence and, last but not least, patient's compliance with antiretroviral therapy [7].…”
Section: Discussionmentioning
confidence: 99%