Suspected case of COVID-19-associated pancreatitis in a child

Alloway, Brian C.; Yaeger, Susan K.; Mazzaccaro, Richard J.; Villalobos, Tibisay; Hardy, Steven G.

doi:10.1016/j.radcr.2020.06.009

Cited by 36 publications

(39 citation statements)

References 9 publications

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“…The association of pancreatitis and COVID-19 infection has been suggested over the past several months with a few case reports, but there has only been 1 report of pancreatitis in a child to our knowledge. Unlike our patients, the 7-year old in the previous case report presented with necrotizing pancreatitis 2 weeks prior to her COVID-19 diagnosis [ 2 ]. Pancreatitis has been reported in several viral diseases, including mumps, measles, Epstein-Barr virus, hepatitis A and E, and Coxsackievirus [ 1 , 3 ], thus making the association between SARS-CoV-2 and pancreatitis plausible.…”

Section: Discussionmentioning

confidence: 79%

Pancreatitis in Pediatric Patients With COVID-19

Samies

Yarbrough

Boppana

2020

Journal of the Pediatric Infectious Diseases Society

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Section: Discussionmentioning

confidence: 79%

Pancreatitis in Pediatric Patients With COVID-19

Samies

Yarbrough

Boppana

2020

Journal of the Pediatric Infectious Diseases Society

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“…Most of these cases had severe COVID-19 infection at baseline. However, a few of these cases had no respiratory symptoms to start with [ [39] , [40] , [41] ]. One of the initial reports was that of development of AP in 2 out of 3 COVID-19 positive hospitalized members of a family in Denmark [ 42 ].…”

Section: Real World Data Of Covid-19 and Pancreatic Injurymentioning

confidence: 99%

“…Alloway et al. [ 39 ] reported a case of a 7-yr-old girl with AP without any respiratory symptoms at onset. On evaluation, she was found to be COVID-19 positive.…”

Section: Real World Data Of Covid-19 and Pancreatic Injurymentioning

confidence: 99%

“…[ 52 ](USA) Case report ✚ ✚ Normal Clinical AP Alloway et al. [ 39 ] Case report ✚ ✚ suggestive of necrotising pancreatitis 7-yr-old girl with AP; No respiratory symptoms to begin with Miao et al. [ 41 ](France) Case report ✚ ✚ Enlarged pancreas No respiratory symptom with clinical AP Anand et al.…”

Section: Real World Data Of Covid-19 and Pancreatic Injurymentioning

confidence: 99%

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Coronavirus disease 2019 and the pancreas

et al. 2020

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Coronavirus disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has led to a world-wide pandemic since its onset in December of 2019. Although, a primary respiratory pathogen, over the ensuing period, its extra-pulmonary effects have come to the forefront. The virus, having multi-organ tropism, has been shown to affect a host of other organs beyond the lung, including the pancreas. The data on pancreatic involvement by COVID-19, however, have been limited. Moreover, whether the effects on the pancreas are due to the direct effects of the virus or is just an epi-phenomenon is debatable. The prevalence of pancreatic injury and degree of injury are the other issues that need to be addressed. Pancreatic cancer has a dismal prognosis and the management of the same in the COVID era needs to be tailored assessing the risk-benefit ratio for the same. Additionally, pancreatic surgery increases not only the morbidity of the patient, but also the risk of the operator and burden on the health care system. Hence, the decision for such major procedures needs to be rationalized for optimum benefit during this pandemic. Similarly, for the endoscopist, pancreatic endoscopy needs to be carefully regulated to reduce risk to both the patient and the physician and yet deliver optimum patient care. This review gives a concise summary of various aspects of pancreatic involvement and pancreatic disease management during this pandemic.

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“…In that study, idiopathic pancreatitis was statistically the most common etiology in COVID-19 patients and thus implicates SARS-CoV-2 in a causative role for acute pancreatitis. Although various case reports exist [ [2] , [3] ] [ [2] , [3] ], no study to date has examined the association or prevalence of pancreatitis in children with COVID-19. Our study aimed to identify the point prevalence of acute pancreatitis within pediatric patients hospitalized in our large healthcare system in New York between March and June 2020, as well as describe the characteristics of these patients.…”

Section: Introductionmentioning

confidence: 99%