Sustainable nanofibers in tissue engineering and biomedical applications

Abstract

The practice of using a massive amount of environmental unfriendly and toxic petroleum-based materials in tissue engineering and biomedical fields demands the materials, which are biodegradable, renewable, environmentally friendly, biocompatible, and bioactive. So, renewable polymers have got considerable attention due to their numerous desirable properties. The nanofibers that are prepared from renewable materials and their blends can integrate the properties of both nanofibers and renewable polymers. Development of scaffolds that mimic the construction of tissues at nanoscale is a great challenge for tissue engineering. Electrospinning is the most promising technique for nanofibers formation. Nanofibers provide a platform for cell adhesion, proliferation, and differentiation. Therefore, nanofibers from sustainable materials have been used in tissue engineering and biomedical fields. In this review, methods for nanofibers fabrication, sustainable nanofibers made from natural and synthetic polymers and their applications in tissue engineering and biomedical field, have been emphasized.

Sustainable Applications of Nanofibers in Agriculture and Water Treatment: A Review

“…Chemical (acetylation, alkaline, benzoylation, peroxide, potassium permanganate, silane, and stearic acid) and surface treatments [1] Non-electrospinning techniques (i.e., phase separation, drawing, template synthesis, and self-assembly), electrospinning, and hydrothermal techniques [35][36][37][38]…”

“…Several studies reported about different applications of the nanofibers in medical sectors, such as Malik et al [37], de 6. The healing process of bones and tendons is very slow, and The application of nanofibers or with some bioactive compounds is increasing in medicine as drug release capsule; transdermal absorbent; drug release artificial skin; wound dressing; artificial blood vessel; covered stent; artificial cornea; artificial skin; filling agent for artificial bone, wound, and therapeutic applications; nerve or organ patch wound covering and protective agent; dialysis membrane; surgical adhesive sheet; and adhesion prevention materials [63].…”

“…Several studies reported about different applications of the nanofibers in medical sectors, such as Malik et al [37], de Carvalho and Conte-Junior [128], Ghajarieha et al as in the pharmaceutical applications, for example, Imani et al [134], Balusamy et al [135], Dodero et al [136], Kumar et al [137], Haidar et al [138], and Pandey [139], as listed in Table 6. The healing process of bones and tendons is very slow, and depending on the severity of the injures, it takes at least six weeks or more for them to regain normal alignment.…”

Nanofibers for Sustainable Agriculture: A Short Communication

“…Nanofibers are nanotechnological products, which could be defined as one-dimensional nanomaterials whose diameter range from tens to hundreds of nanometers and are produced using a broad range of natural, synthetic, and hybrid polymers (Bose 2021). The main methods for producing the nanofibers may include nonelectrospinning techniques (i.e., phase separation, template synthesis, drawing, and self-assembly), electrospinning and hydrothermal techniques (Malik et al 2020;Naidu et al 2021). Nanofibers have many benefits that can use in several fields in our life (Table 1).…”

Graphene Oxide–Protein-Based Scaffolds for Tissue Engineering: Recent Advances and Applications

“…Over the past decades, significant efforts have been dedicated to replicating the mechanical integrity, morphology, and architecture of real natural human tissue, particularly by developing new preparation techniques and reinforcing protein-based scaffolds with nanomaterials that mimic native tissue environments to improve tissue growth, differentiation, proliferation, cellular signaling, etc. The introduction of nanofibers, nanoparticles, nanotubes, or other inorganic carriers [25][26][27][28] was found to be highly efficient for mediating tissue formation.…”