Sustainable spectrophotometric determination of antihypertensive medicines reducing COVID-19 risk via paired wavelength data processing technique - Assessment of purity, greenness and whiteness

Greenness‐by‐design approach for developing novel UV spectrophotometric methodologies resolving a quaternary overlapping mixture

“…Univariate spectroscopic methods alone [ 27 ] may find it difficult to resolve multicomponent combinations with significant signal interference on their overlain spectra, as shown in Figure 1a, for the investigated combination. A possible solution is to couple more than one univariate method in a rational order to resolve some complex mixtures.…”

“…A possible solution is to couple more than one univariate method in a rational order to resolve some complex mixtures. [27,28] The rational coupling of univariate spectroscopic methods can treat a complex mixture on several levels, applying a suitable spectrophotometric method at each level to resolve one or two components of the mixture. Another powerful tool to tackle this problem is chemometrics, which can resolve spectrum interference using statistical and mathematical approaches.…”

Spider diagram and sustainability evaluation of UV-methods strategy for quantification of aspirin and sildenafil citrate in the presence of salicylic acid in their bulk and formulation

“…In the light of green analytical chemistry (GAC) [ 25 ], UV-methods provide economic green analytical methods instead of chromatographic ones, because they do not use more solvents, do not generate a lot of waste, and do not need additional equipment. So they are considered as cost-saving methods [ [26] , [27] , [28] , [29] , [30] , [31] ].…”

Coupling of physical extraction and mathematical filtration in spectrophotometric analysis of natural therapy essential for prophylaxis and treatment of COVID-19 infection - Comparative study along with greenness evaluation

“…3 a. The FR ΔA S was assured factual as the absorbance difference between 367.3 nm and 266.5 nm in the produced spectrum was equals to one (1) [ 46 ]. The D 0 spectra of DIO were accomplished via multiplication of the obtained FR ΔA S by the absorbance difference of (A 367.30nm – A 266.50nm ) of each laboratory provided mixtures where the concentration of DIO in each laboratory provided mixtures was computed via substitution in its regression equation in zero order which shows a linear correlation at 372.0 nm for DIO versus its correspondent concentrations in the range (7.0–70.0 μg/mL) as shown in Fig.…”