The output of municipal solid waste is growing rapidly, which has brought tremendous pressure to urban development. The supply chain of municipal solid waste (MSW) in China mainly contains three processes: collection, transportation, and disposal. The waste is sorted at the collection and disposed of according to the classification. However, it is mixed at the transportation stage. Mixed transportation remixes the separately collected waste, which seriously affects the disposal effect. The supply chain of MSW urgently needs to be redesigned to improve the MSW disposal effect. First of all, on the ground of the waste treatment situation, we redesigned the supply chain of MSW in China. Secondly, combined with the redesign of the MSW supply chain, this paper established the function allocation model for collection stations, making a collection station only gather one type of waste, and built the transportation path planning model for vehicles, reducing the impact of waste storage on residents. Finally, based on the data of Xuanwu District in Beijing, the supply chain redesigning practical example of incinerable waste was given. The supply chain redesigning model in this paper not only makes full use of the existing infrastructure but also improves the disposal effect of waste. The supply chain redesigning model has practical application value.