Sustaining the Transition from a Petrobased to a Biobased Chemical Industry with Flow Chemistry

Innovative Protocols in the Catalytic Oxidation of 5‐Hydroxymethylfurfural

“…The combination of a variety of popular biomass-based platform molecular valorization reactions have been investigated under continuous-flow conditions. [91,92] Several Pt-based catalyst were investigated initially for the oxidation of HMF in continuous-flow regime; 5 % Pt/C in a tubular fixed-bed reactor afforded 60 % FDCA yield and 38 % FFCA yield at 100°C under 40 bar of O 2 pressure. [93] Furthermore, Pt/C as catalyst under basic, neutral, as well as acidic feed environment was examined in continuous-flow regime, [94] where basic conditions favored the formation of FDCA and quantitative HMF conversion with 95 % FDCA yield was obtained under optimum conditions.…”

Towards highly efficient continuous-flow catalytic carbon dioxide cycloadditions with additively manufactured reactors

“…[5][6][7][8] Compared to batch systems, continuous-flow catalytic systems improve mixing, manage heat transfer more efficiently, increase the catalytic performance by improving the contact between the phases, increase productivity by continuously adding reagents and removing products from the reactor and generally speaking provide a more reproducible, scalable, safe and efficient option for performing chemical reactions, which make it an industrially attractive technology. [9][10][11][12][13] The design and manufacture of efficient and scalable catalytic reactors is highly challenging. 14 Indeed, the fabrication of fixed-bed catalytic reactors faces several challenges to balance the process efficiency with mass and heat transport limitations.…”

Microwave-Assisted Lignin Wet Peroxide Oxidation to C4 Dicarboxylic Acids

“…12,13 Recently, an increased interest in C 4 dicarboxylic acids (C 4 -DCA) like succinic, maleic, and fumaric acids, arose given their current industrial use and prospects as future biomass-based building blocks. 14,15 It is necessary to use harsh reaction conditions to achieve an aromatic ring-opening reaction, namely, strong oxidants (usually H 2 O 2 , O 3 , or organic peroxides) assisted by heterogeneous catalysis. 5 Traditionally, oxidative conversion of lignin has been carried out using conventional heating (CH), usually by applying high temperatures and pressures, and toxic or expensive solvents and catalysts.…”