The flow regime of the Danube in the area of the middle part of the basin, on the section of the Danube through Croatia and Serbia, was analyzed. This paper contains a hydrological analysis of the Danube regime using measured flow data at four regression stations; Batina in the Republic of Croatia, and the regression stations Bezdan, Bogojevo and Smederevo in the Republic of Serbia for the period 1992-2018. On this section, two large rivers, the Drava and the Sava, flow into the Danube, which significantly affect the Danube regime. Parde's method of modular coefficients was used to classify the flow regime. Comparing the curves of mean monthly flows expressed through modular coefficients for the Danube, Drava and Sava, it can be concluded that the Danube has an alpine snow regime at the top of the analyzed section, just like the Drava that flows into the Danube. At the regression station Smederevo, the curve of mean monthly flows expressed in modular coefficients is similar to the curve for the Sava, which flows into the Danube upstream from Smederevo, and the Danube has a combined flow regime like the Sava.