Swarna Bhasma in cancer: A prospective clinical study

Das, Sudipta; Das, Mangal C; Paul, Retina

doi:10.4103/0974-8520.108823

Cited by 27 publications

(12 citation statements)

References 7 publications

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“…It is an alternative, aphrodisiac, anti-pyretic, carminative, hematinic and proven rejuvenator [3][4][5]. According to some new findings, bhasma are claimed to be biologically produced nanoparticle using Ayurvedic methods [6][7][8]. The details of Ayurvedic methods for preparation of Abhrakh bhasma are explained in detail Ayurvedic text [9][10].…”

Section: Introductionmentioning

confidence: 99%

Study on physical properties of Indian based ayurvedic medicine: Abhrakh bhasma as nanomaterials by employing modern scientific tools

Kumar

et al. 2018

GSC Biol. and Pharm. Sci.

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Abhrakh bhasma is an Ayurvedic medicine widely used for treating several diseases such as; pernicious, sickle cell anemia, Bell's palsy, hepatic dysfunction, leukemia, sex debility, cystic fibrosis, post encephalic dysfunction and cervical dysplasia etc. An Ayurveda bhasma is a medicine, which is used since ancient time and claimed to be very useful medicine at Nano metric scale. However there is a need of scientific evidence of such Ayurvedic products using modern scientific techniques of 21 st century. The physical behavior was measured by X-ray diffractometer (XRD), fourier transform spectroscopy (FTIR), vibrating sample magnetometer (VSM), scanning electron microscopy (SEM), and photoluminescence (PL) spectrometer. Abhrakh bhasma is prepared by using mica as a base materials. X-ray diffraction and SEM analysis revealed that this bhasma is in nanocrystalline form and, can be considered as nanomedicine. Magnetic hysteresis (M~H) loop study by using the VSM reveals the super paramagnetic nature. Luminescence in bhasma was observed in visible region upon excitation of 200 nm laser source. This investigation reveals that, the Abhrakh bhasma may not only used as nanomedicine but also can be employed a materials for various other technological applications due to both magnetic as well as luminescence properties. Preliminary testing of Abhrakh bhasma nanoparticles was examined on Staphylococcus aureus and Escherichia coli bacteria.

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Section: Introductionmentioning

confidence: 99%

Study on physical properties of Indian based ayurvedic medicine: Abhrakh bhasma as nanomaterials by employing modern scientific tools

Kumar

et al. 2018

GSC Biol. and Pharm. Sci.

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“…3. 'Swarna Bhasma' has shown some response in the treatment of solid tumor 35 , and some herbominerals preparations were effective towards leukemia 36 37 and antioxidant/restorative effects against global and focal models of ischemia (stroke).…”

Section: Bhasmas In Therapeuticsmentioning

confidence: 99%

Analytical Methods in Standardization of Bhasmas: A Review

Yadav

Gananadhamu

et al. 2021

J. Drug Delivery Ther.

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Ayurveda the ancient science well known for its potential therapeutic effects with unique metallic, herbal juices/fruits in the treatment of chronic ailments. A well- known ayurvedic potent preparation, Bhasma is also known as ash which is a metallic base prepared by sophisticated pharmaceutical processes also plays a major role in acute, sub-acute, and chronic diseases. In order to determine its quality and purity to make sure the acceptability, the safety of the formulation standardization is very necessary. In this short review, an attempt has been made to present ancient methods to standardize physical characterstics like Verna, Nisvadutam, Nishchandratvam, Varitara, Unama, Rekhapurmatvam, Slakshmatvam..etc.,and chemical characterstics of bhasmas like Apurnabhavta, Niruttha, Amla Pariksha with advanced methods like SEM, TEM, and NPST, along with other natural and ancient analytical techniques. Keywords: Bhasmas, Standardization, Analytical methods, SEM, TEM.

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“…Another clinical study of Kukkutanda twak bhasma reveals statistically significant improvement in Swetapradara, an important gynecological disorder [12]. Likewise, 'Swarna Bhasma' has shown some response in the treatment of solid tumor [13], and certain herbo-minerals preparations were found to be effective in leukemia [14,15]. Swarna Bhasma also has antioxidant/restorative effects against global and focal models of ischaemia (stroke).…”

Section: Therapeutic Use Of Bhasmasmentioning

confidence: 99%

The Ayurvedic Bhasma: The Ancient Science of Nanomedicine

Pal

2015

PNM

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Nanomedicine is the relevance of nanotechnology in the area of healthcare, diagnosis of disease, cure and prevention of disease. Nanotechnology covers the diverse area of matters at dimensions between approximately 1 to 100 nanometers. Nanotechnology has enormous applications in drug delivery field. Nano drug delivery systems can reduce the drug consumption and side-effects by lowering the deposition of the active agent in the non targeted sites. Ayurveda is thousands of years old holistic system of Indian medicine. Various herbs, metals and non-metals preparations are used as medicine in Ayurveda. In the Ayurvedic description, several metallic preparations called Bhasma are in clinical use since 8th century AD. The Puta system of Ayurveda describes that metals or minerals should be heated at high temperature for melting and then it quench in suitable media like herbal juices or decoction for specified times. The Bhasma (incinerated metals) is obtained by repeating these methods several times. In this process the toxic effects of the metals are not only nullified but are transformed into biologically active nanoparticles. When various Bhasmas viz. Swarna bhasma, Makshika bhasma, Abhrak bhasma, Tamra bhasma and Louha bhasma were subjected to analysis under electron microscope it was found that they were similar to nanocrystalline materials possessing similar physico-chemical properties. The therapeutic effect of Bhasma may be attributed to large surface area of materials and small particle size by which they can easily transported into cell nucleus and to specific target sites as desired.

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Swarna Bhasma in cancer: A prospective clinical study

Cited by 27 publications

References 7 publications

Study on physical properties of Indian based ayurvedic medicine: Abhrakh bhasma as nanomaterials by employing modern scientific tools

Study on physical properties of Indian based ayurvedic medicine: Abhrakh bhasma as nanomaterials by employing modern scientific tools

Analytical Methods in Standardization of Bhasmas: A Review

The Ayurvedic Bhasma: The Ancient Science of Nanomedicine

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