“…Daily hassles are the minor, frequently occurring challenges of daily life, such as household chores or having a disagreement with a family member (Almeida, 2005;Bolger, Delongis, Kessler, & Schilling, 1989;McIntyre, 2008) that have immediate, direct effects on health and well-being (Bolger, Davis, & Rafaeli, 2003). The chronic experience of stress, such as that which may occur in response to continued daily stress within the context of widowhood may lead to increased proinflammatory cytokines (Kiecolt-Glaser, McGuire, Robles, & Glaser, 2002) and an overactivation and dysregulation of the body's stress response that may result in a decreased ability to respond to stress and potentially negative health outcomes (Finch & Seeman, 1999).…”