Sweet's syndrome (acute febrile neutrophilic dermatosis)

Driesch, Peter Von Den

doi:10.1016/s0190-9622(94)70215-2

Cited by 650 publications

(456 citation statements)

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“…18 Further, concurrent with medical literature, more severe and atypical forms were noted in necrotic and purpureal vesicular lesions with bullas on the trunk, backs of hands, and lower limbs. 2,4,5 In cases # 2 and # 7, lesions were observed on labial semi-mucosa, and in case # 6, on jugal and vulvar mucosas.…”

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confidence: 60%

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Síndrome de Sweet asociado a neoplasias

Franco

Giusti

Malieni

et al. 2006

An. Bras. Dermatol.

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Sweet's syndrome was described in 1964 by Robert Douglas Sweet, as an entity he named acute febrile neutrophilic dermatosis. It is characterized by five main features: 1) sudden appearance of erythematous and tender plaques on the face, neck and extremities; 2) fever; 3) polymorphonuclear leukocytes; 4) predominantly neutrophilic dense infiltrate in the dermis, and 5) rapid response to steroid therapy. Sweet's syndrome can be classified into five groups: idiopathic, parainflammatory, paraneoplastic, drug-induced, and pregnancy-related. Twenty percent of cases are associated with malignancies; 85% out of them involve hematologic alignancies and the remaining 15%, solid tumors. A series of seven cases of Sweet's syndrome associated with neoplasms which were diagnosed from 2002 to 2006 is presented. Six cases were related to oncohematologic diseases and one to solid tumors. These results highlight the importance of the diagnosis of the syndrome, since it may predict tumor relapse or underlying disease progression. The timely use of diagnostic and treatment methods may improve the quality of life of these patients. The fact that oncology patients take multiple medications (a colony-stimulating factor) which may be associated with the onset of this entity must also be considered in excluding possible causes. Keywords: Prognosis; Skin Neoplasms; Sweet's syndrome

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confidence: 60%

“…2,5,18 The patient with multiple myeloma experienced central facial paralysis with no changes seen on nuclear magnetic resonance of the brain. This patient showed improvement coinciding with the involution of the skin lesions.…”

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Síndrome de Sweet asociado a neoplasias

Franco

Giusti

Malieni

et al. 2006

An. Bras. Dermatol.

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“…Oral ulceration similar in clinical appearance to RAS can arise in Sweet's Syndrome (Delke et al, 1981;Driban and Alvarez, 1984;Mizoguchi et al, 1988;von den Driesch et al 1989von den Driesch et al , 1994; cyclic neutropenia (Lange and Jones, 1981;Scully et al, 1982); benign familial neutropenia (Porter et al, 1994a); MAGIC Syndrome (Orme et al, 1990;Godeau, 1993;Le Thi Huong et al, 1993), a periodic syndrome with fever and pharyngitis (Marshall et al, 1987); various nutritional deficiencies with or without underlying gastrointestinal disorders (Eversole, 1994;Grattan and Scully, 1986); and some other primary (Porter and Scully, 1993a,b;Scully and Porter, 1993a,b) and secondary immunodeficiencies (Porter et al, 1994b), including infection with human immunodeficiency virus (MacPhail et al, 1992). Rarely, drugs such as non-steroidal anti-inflammatories (NSAIDS) can give rise to oral ulcers similar to those of RAS, along with genital ulceration (Healy and Thornhill, 1995).…”

Section: Clinical Featuresmentioning

confidence: 99%

Recurrent Aphthous Stomatitis

Porter

Scully

Pedersen

1998

Critical Reviews in Oral Biology & Medicine

252

143

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“…Our patient met the criteria for SS developed by Su and Liu and modified by von den Driesch [11][12]. In addition to the two major criteria (abrupt onset of tender or painful erythematous or violaceous plaques or nodules and neutrophilic infiltration of the dermis without leukocytoclastic vasculitis), he had three minor criteria (elevation of the CRP level, leukocytosis and preceding slight fever) [2].…”

Section: Discussionmentioning

confidence: 88%

“…Differences between Behçet's disease and SS include predominant skin involvement in SS, with oral ulcers in only 3-30% of cases [13], and a distinctive clinical course [14]. Genital ulcers are exceedingly rare in Sweet's syndrome [12]. Among the extra cutaneous manifestations of SS, joint involvement, which is found in 33-62% of cases, consists chiefly of asymmetric polyarthralgia without joint destruction [15].…”

Section: Discussionmentioning

confidence: 99%

Sweet’s syndrome revealed by oral pustulosis

Fricain

Sibaud

Lepreux

et al. 2015

Med Buccale Chir Buccale

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-Introduction:Neutrophilic dermatoses are conditions characterized by a dermal neutrophilic infiltration associated with variable leukocytoclasia. Oral involvement occurs but is rare and is of less importance than the cutaneous involvement. Observation: The case of a 71-year-old man with neutrophilic dermatoses in whom the major manifestations of the disease were recurrent oral ulcers associated with tongue pustulosis is reported. Oral and skin biopsies revealed a dense neutrophilic infiltrate in the lamina propria. Clinical symptoms were quickly resolved with colchicine treatment. The clinical course allowed us to diagnose Sweet's syndrome associated with oral pustulosis. Discussion: The main differential diagnosis of Sweet's syndrome is from Behçet's disease. Overlap exists between the manifestations of the two diseases, so they must be differentiated. The recurrence of oral ulcers with little inflammatory halo and the quick resolution of ulcers associated with pustules, as well as the histological patterns, were not compatible with Behçet's disease. Résumé -Introduction :Les dermatoses neutrophiles sont caractérisées par une infiltration neutrophilique cutanée associée à une leucocytoclasie. Les manifestations orales sont rares et moins bruyantes qu'au niveau de la peau. Observation : Le cas d'un homme de 71 ans avec une dermatose neutrophile dont les principales manifestations de la maladie étaient des ulcères buccaux récurrents associés à une pustulose linguale est rapporté. Les biopsies buccales et cutanées ont révélé un infiltrat neutrophilique dense dans la lamina propria. Les symptômes cliniques ont été rapidement résolus avec de la colchicine. L'évolution clinique a permis de diagnostiquer un syndrome de Sweet associé à une pustulose orale. Discussion : Le principal diagnostic différentiel du syndrome de Sweet est la maladie de Behçet. Des chevauchements existent entre les manifestations cliniques des 2 entités. Mais celles-ci n'ont pas le même pronostic et doivent être différenciées. La récurrence des ulcères buccaux avec un discret halo inflammatoire, la résolution rapide des ulcères associés aux pustules ainsi que les aspects histologiques du cas décrit, n'étaient pas compatibles avec la maladie de Behçet.

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Sweet's syndrome (acute febrile neutrophilic dermatosis)

Cited by 650 publications

References 202 publications

Síndrome de Sweet asociado a neoplasias

Síndrome de Sweet asociado a neoplasias

Recurrent Aphthous Stomatitis

Sweet’s syndrome revealed by oral pustulosis

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