The 16 O(e,e 0 p) reaction was studied in the rst physics experiment performed at Je erson lab Hall A. In the quasielastic region cross sections were measured for both quasi-parallel and perpendicular kinematics at q = 1 0 0 0 M e V a n d ! =445 MeV. From the data acquired in quasi-parallel kinematics, longitudinal and transverse response functions, R L and R T were separated for E miss < 60 MeV. The perpendicular kinematics data were used to extract R LT , R T , a n d R L + VT T VL R T T response functions for the same E miss range and for P miss < 310 MeV/c. The 16 O(e,e 0 p) cross section was measured in the dip region at q = 1026 MeV and ! =586 MeV for 10 MeV < E miss < 320 MeV. This thesis presents the results for the missing energy continuum (E miss > 25 MeV) from this experiment.The measured cross sections and the response functions are compared to DWIA and HF-RPA calculations of the strength for the single particle knockout from the 1s 1=2 shell. For the quasielastic, quasi-parallel kinematics setting, the measured cross sections and the response functions for E miss < 50 MeV are mostly accounted for by the single particle knockout from 1s 1=2 . For 50 MeV < E miss < 60 MeV, R T remains strong while R L appears to go to zero. The di erence between the longitudinal and transverse spectral functions, S T ; S L , which is expected to be zero for a f r e e n ucleon, is close to zero at lower E miss but increases above the two n ucleon emission threshold.The behavior of R L and R T for the j pq j = 8 setting is very similar to that of the quasi-parallel setting: for 50 MeV < E miss < 60 MeV, R L ! 0 while R T remains strong. However R LT is non-zero for 50 MeV < E miss < 60 MeV, indicating that R L might b e small but non-zero in this E miss range.For the quasielastic, j pq j = 1 6 setting, the relative strength in the continuum compared to the strength in the valence states is much higher than at lower P miss settings. Only a small fraction of this continuum strength is accounted for by the calculated 1s 1=2 knockout strength. R T and R LT response functions are also much stronger than the prediction, while the longitudinal response is small as predicted.The cross sections calculated for the quasielastic, j pq j = 2 0 settings show e v en higher relative strengths in the continuum compared to the valence states. The phase space of the pq = ;20 setting extends across the two body correlated ridge and shows an increase in cross section around the location of the ridge.The cross section measured in the dip region exhibits continuum strength up to the highest measured E miss of 320 MeV. An increase in this cross section is observed above the pion production threshold.