Swift fabrication of Ag nanostructures using a colloidal solution of Holostemma ada-kodien (Apocynaceae) – Antibiofilm potential, insecticidal activity against mosquitoes and non-target impact on water bugs

Alyahya, Sami A.; Govindarajan, Marimuthu; Alharbi, Naiyf S.; Kadaikunnan, Shine; Khaled, Jamal M.; Mothana, Ramzi A.; Al-anbr, Mohammed N.; Vaseeharan, Baskaralingam; Ishwarya, Ramachandran; Yazhiniprabha, Mariappan; Benelli, Giovanni

doi:10.1016/j.jphotobiol.2018.02.019

Cited by 17 publications

(4 citation statements)

References 62 publications

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“…stephensi, with LC 50 below 20 μg/mL. Consisting with previous reports on diverse families of plants such as A. raddianum (Pteridaceae), Hugonia mystax (Linaceae), Psidium guajava (Myrtaceae), Holostemma ada-kodien (Apocynaceae) and Aganosma cymosa (Apocynaceae) (Govindarajan et al, 2017a(Govindarajan et al, , 2017bBenelli and Govindarajan, 2017;Alyahya et al, 2018;Ntoumba et al, 2020). In contrast, some authors reported LC 50 > 20 μg/mL for AgNPs fabricated with Ventilago maderaspatana (Rhamnaceae), Naregamia alata (Meliaceae), Hedychium coronarium (Zingiberaceae) and Sargassum wightii (Sargassaceae) (Azarudeen et al, 2017a(Azarudeen et al, , 2017bKalimuthu et al, 2017;Murugan et al, 2017).…”

Section: Figuresupporting

confidence: 58%

Phytofabrication and characterization of Alchornea cordifolia silver nanoparticles and evaluation of antiplasmodial, hemocompatibility and larvicidal potential

Foko

Hawadak²,

Verma³

et al. 2023

Front. Bioeng. Biotechnol.

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Purpose: The recent emergence of Plasmodium falciparum (Pf) parasites resistant to current artemisinin-based combination therapies in Africa justifies the need to develop new strategies for successful malaria control. We synthesized, characterized and evaluated medical applications of optimized silver nanoparticles using Alchornea cordifolia (AC-AgNPs), a plant largely used in African and Asian traditional medicine.Methods: Fresh leaves of A. cordifolia were used to prepare aqueous crude extract, which was mixed with silver nitrate for AC-AgNPs synthesis and optimization. The optimized AC-AgNPs were characterized using several techniques including ultraviolet-visible spectrophotometry (UV-Vis), scanning/transmission electron microscopy (SEM/TEM), powder X-ray diffraction (PXRD), selected area electron diffraction (SAED), energy dispersive X-ray spectroscopy (EDX), Fourier transformed infrared spectroscopy (FTIR), dynamic light scattering (DLS) and Zeta potential. Thereafter, AC-AgNPs were evaluated for their hemocompatibility and antiplasmodial activity against Pf malaria strains 3D7 and RKL9. Finally, lethal activity of AC-AgNPs was assessed against mosquito larvae of Anopheles stephensi, Culex quinquefasciatus and Aedes aegypti which are vectors of neglected diseases such as dengue, filariasis and chikungunya.Results: The AC-AgNPs were mostly spheroidal, polycrystalline (84.13%), stable and polydispersed with size of 11.77 ± 5.57 nm. FTIR revealed the presence of several peaks corresponding to functional chemical groups characteristics of alkanoids, terpenoids, flavonoids, phenols, steroids, anthraquonones and saponins. The AC-AgNPs had a high antiplasmodial activity, with IC50 of 8.05 μg/mL and 10.31 μg/mL against 3D7 and RKL9 Plasmodium falciparum strains. Likewise, high larvicidal activity of AC-AgNPs was found after 24 h- and 48 h-exposure: LC50 = 18.41 μg/mL and 8.97 μg/mL (Culex quinquefasciatus), LC50 = 16.71 μg/mL and 7.52 μg/mL (Aedes aegypti) and LC50 = 10.67 μg/mL and 5.85 μg/mL (Anopheles stephensi). The AC-AgNPs were highly hemocompatible (HC50 > 500 μg/mL).Conclusion: In worrying context of resistance of parasite and mosquitoes, green nanotechnologies using plants could be a cutting-edge alternative for drug/insecticide discovery and development.

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Section: Figuresupporting

confidence: 58%

Phytofabrication and characterization of Alchornea cordifolia silver nanoparticles and evaluation of antiplasmodial, hemocompatibility and larvicidal potential

Foko

Hawadak²,

Verma³

et al. 2023

Front. Bioeng. Biotechnol.

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“…The Green Biosynthesis methods provide benefits against the chemical and physical fabrications methods, but it does not require any special chemicals, harmful chemicals, and high energy inputs (Kathiraven et al, 2015;Govindrajan et al, 2016). In general, the green synthesis methods are inexpensive, easily synthesized and conducted for the rapid formation of silver nanoparticles (Azarudeen et al, 2017;Alshehri et al, 2018;Alyahya et al, 2018;Sinha and Manjihi, 2015).…”

Section: Discussionmentioning

confidence: 99%

Sargassum swartzii: A source of silver nanoparticles, synthesis and its antibacterial activity

Solanki

Patel²

2022

Egyptian Journal of Agricultural Research

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In current trends of green synthesis of nanoparticles is rapidly shifting from plants based to marine algae as it is widely available as well as highly explore for pharmaceutical work. Presented work focuses on synthesising silver nanoparticles using marine algae Sargassum swartzii and its characterization through multiple authentic methods like UV-Vis spectrophotometer, X-Ray Diffraction, Fourier transform infrared spectroscopy, Scanning Electron Microscopy and Transmission Electron microscopes.The primary confirmation was done by the visible appraisal of the color difference from the light yellow-brown to dark brown colour. The UV-Visible absorbance spectra verified the formation of silver nanoparticles and spectra increased with incubation time. The Surface Plasmon Resonance (SPR) absorbance peak was observed at 439nm. SEM and TEM confirmed particles' surface morphology and size of AgNPs from 14 to 30nm. XRD approved particles' face-centric cubic and crystal structure and the size (15.33 nm) calculated through the Scherer equation. FTIR analysis reflected the various functional groups associated with the algal extracts, which help in the bindings of Ag molecules during AgNPs synthesis. The synthesized silver nanoparticles revealed significant antibacterial activity against Bacillus subtilis (27.17±0.73mm) and Staphylococcus aureus (23.53±0.29mm). The work reported that Sargassum swartzii widely available brown macroalgae, could be used as an alternative source for synthesis of AgNPs without destroying high plants and the produced AgNPs have efficient antibacterial activity against both gram positive and gram negative bacteria, which can be explore in curing several human diseases.

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“…[ 78 , 79 , 80 ]. Also, it shows antimicrobial [ 64 , 81 , 82 , 83 ], and acaricidal [ 84 ] effects.…”

Section: Plants and Nano Formulationsmentioning

confidence: 99%

“…Using plant extracts to synthesize NPs increases the mortality rate of mosquitoes in all developmental stages, and this effect is obtained using lower concentrations of the extract. For example, Ag NPs synthesized with Euphorbia hirta [ 124 ], Nerium oleander [ 125 ], U. lactuca [ 97 ], Codium tomentosum [ 114 ], M. sylvestris [ 108 ], Holostemma adakodien [ 81 ], H. mystax [ 104 ], Quisqualis indica [ 130 ], Nicandra physalode [ 131 ], Gmelina asiatica [ 132 ], Musa paradisiaca [ 149 ], Drypetes roxburghii [ 150 ], Vinca rosea [ 151 ], Cocos nucifera [ 112 ], Pergularia daemia [ 152 ], L. siceraria ZnO NPs [ 99 ], and C. citratus Au NPs [ 100 ] had the highest larvicidal and pupicidal effect against A. stephensi , in comparison to the crude plant extract. S. xanthocarpum -synthesized Ag NPs showed significant larvicidal effects up to 72 h after A. stephensi larvae exposure [ 105 ].…”

Section: Antimalarial Effects Of Green Npsmentioning

confidence: 99%

Tiny Green Army: Fighting Malaria with Plants and Nanotechnology

Moraes-de-Souza,

de Moraes,

Silva

et al. 2024

Pharmaceutics

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Malaria poses a global threat to human health, with millions of cases and thousands of deaths each year, mainly affecting developing countries in tropical and subtropical regions. Malaria’s causative agent is Plasmodium species, generally transmitted in the hematophagous act of female Anopheles sp. mosquitoes. The main approaches to fighting malaria are eliminating the parasite through drug treatments and preventing transmission with vector control. However, vector and parasite resistance to current strategies set a challenge. In response to the loss of drug efficacy and the environmental impact of pesticides, the focus shifted to the search for biocompatible products that could be antimalarial. Plant derivatives have a millennial application in traditional medicine, including the treatment of malaria, and show toxic effects towards the parasite and the mosquito, aside from being accessible and affordable. Its disadvantage lies in the type of administration because green chemical compounds rapidly degrade. The nanoformulation of these compounds can improve bioavailability, solubility, and efficacy. Thus, the nanotechnology-based development of plant products represents a relevant tool in the fight against malaria. We aim to review the effects of nanoparticles synthesized with plant extracts on Anopheles and Plasmodium while outlining the nanotechnology green synthesis and current malaria prevention strategies.

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Swift fabrication of Ag nanostructures using a colloidal solution of Holostemma ada-kodien (Apocynaceae) – Antibiofilm potential, insecticidal activity against mosquitoes and non-target impact on water bugs

Cited by 17 publications

References 62 publications

Phytofabrication and characterization of Alchornea cordifolia silver nanoparticles and evaluation of antiplasmodial, hemocompatibility and larvicidal potential

Phytofabrication and characterization of Alchornea cordifolia silver nanoparticles and evaluation of antiplasmodial, hemocompatibility and larvicidal potential

Sargassum swartzii: A source of silver nanoparticles, synthesis and its antibacterial activity

Tiny Green Army: Fighting Malaria with Plants and Nanotechnology

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