Symbiotic effect of Aloe vera juice on the growth of Lactobacilllus fermentum and L. helveticus isolates in vitro

Epigenetic Roles of Microbiota and Aloe vera in Health and Disease

“…Tsai et al [25] who investigated gastrointestinal tract microbiota's critical role in the development of obesity, identified lactic acid bacteria as the likely candidate responsible for the anti-obesity effect. In our previous report, we described the innovative approach on the symbiotic effect by blending Lactobacillus fermentum into aloe vera juice to yield lactic acid, acetic acid, and propionic acid in the fermentation extract [26] . Mollica et al [27] demonstrated that hepatic mitochondria were identified as the main target of the beneficial effect of butyrate in attenuating insulin resistance and fat accumulation in diet-induced obese mice.…”

Prophylactic Aloe Components on Autoimmune Diseases: Barbaloin, Aloe-Emodin, Emodin, and Fermented Butyrate

“…The prebiotic activity of AVJ can be identified by the participation of SCFAs during 24h-incubation with L. fermentum. An innovative concept of symbiosis is perspective for future intestinal health claims to target health and possible anti-inflammatory effects of AVJ supplementation [7] . It is interesting to speculate that such a rather simple dietary intervention might have the prophylactic effect on inflammatory diseases and autoimmunity.…”

“…Endophytes, endogenous microorganisms include bacteria and fungi living within plant tissues without causing any overt negative effects. It is important to note that endophytic bacteria in Aloe vera gel provided butyric acid in in vitro fermented broth extract [7,8] , which will be described in the later section.…”

Dietary ALoe vera gel and Microbiota Interactions: Influence of Butyrate and Insulin Sensitivity

“…They concluded that the symbiotic could lead to potentially beneficial effects to host health by targeting specific bacterial groups, increasing saccharolytic fermentation and decreasing inflammation associated with ageing. In our early report [48] , symbiotic effect of Aloe vera juice on growth of Lactobacillus fermentum, acetic, propionic and lactic acid were identified as short chain fatty acid (SCFA), and only butyric acid was found in the fermented broth of Aloe vera leaf gel with endophytic bacteria. Yadav H group [49] demonstrated that the administration of a probiotic, VSL#3, containing few strains of Lactobacillus and Bifidobacterium, prevented and treated obesity and diabetes in several mouse models.…”