2006
DOI: 10.1002/ejic.200600282
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Symmetrisation in the Interaction of Chloro[2‐(dimethylaminomethyl)phenyl‐C1]mercury(II) with Thiosemicarbazone Derivatives of Pyridine‐2‐carboxamide and Pyrazin‐2‐carboxamide

Abstract: Pyridine‐ and pyrazine‐2‐carboxamide thiosemicarbazones (HAm4DH and HAmpz4DH) or their N4,N4‐dimethyl derivatives (HAm4DM and HAmpz4DM) react with chloro[2‐(dimethylaminomethyl)phenyl‐C1]mercury(II), [Hg(damp)Cl], to give the tetrahedral [Hg(TSC)2] complexes [TSC = Am4DH (1), Am4DM (2), Ampz4DH (3) or Ampz4DM (4)]. Spectroscopic studies and a X‐ray structural analysis show that the potentially tridentate thiosemicarbazones adopt S,N coordination modes, with each deprotonated thiosemicarbazone binding to the Hg… Show more

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Cited by 22 publications
(9 citation statements)
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References 32 publications
(31 reference statements)
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“…4). The shift in chloroform is similar to those observed in other thiosemicarbazonate complexes containing a penta-coordinated mercury atom [22,34,36], and agrees with a dinuclear structure with a sulfur atom acting as a bridge between to metal centers, in which the mercury atom is penta-coordinated. This bridge should be broken in DMSO-d 6 since the signal is shifted to lower field, suggesting a lower coordination number.…”
Section: Spectroscopic Studiessupporting
confidence: 82%
See 1 more Smart Citation
“…4). The shift in chloroform is similar to those observed in other thiosemicarbazonate complexes containing a penta-coordinated mercury atom [22,34,36], and agrees with a dinuclear structure with a sulfur atom acting as a bridge between to metal centers, in which the mercury atom is penta-coordinated. This bridge should be broken in DMSO-d 6 since the signal is shifted to lower field, suggesting a lower coordination number.…”
Section: Spectroscopic Studiessupporting
confidence: 82%
“…The 199 Hg NMR is a useful tool to determine the metal environment, since the chemical shift is very sensitive to its coordination sphere. According to the literature, a decrease in the coordination number gives a greater deshielding [31][32][33][34][35] and therefore higher chemical shifts. The spectrum of complex 2 shows one signal at À917.8 ppm in DMSO-d 6 and at À898.3 ppm in DMF/CDCl 3 (Fig.…”
Section: Spectroscopic Studiesmentioning
confidence: 98%
“…For the isotypic Zn and Hg analogues, see: Fun et al (2008); Islam et al (2012). For the coordination behaviour of metal ions (Co, Ni, Cu, Zn, Cd and Hg) with the cinnamaldehyde Schiff base of S-methyldithiocarbazate, see: Liu et al (2009); Abram et al (2006). For the bioactivity of transition metal complexes of similar Schiff base ligands, see: Chew et al (2004); How et al (2008); Maia et al (2010).…”
Section: Related Literaturementioning
confidence: 99%
“…Various well known chelating agents such as D-penicillamine (H 2 Pen@HSC(CH 3 ) 2 -CH(NH 3 ) + COO À ) and BAL (2,3-dimercaptopropanol) have been clinically used for detoxification and efficiently reduce plasma levels of Hg(II) [19][20][21]. Often, very stable forms include linear complexes with two sulfur ligands; nevertheless, the Hg-S bonds are labile and for higher coordination numbers the structures are flexible, often with distorted trigonal or tetrahedral coordination geometries [22][23][24][25][26]. However, limited number of Hg(II) and phynylmercury complexes with thiosemicarbazones are known, although they are good chelating candidate for this metal ion [22][23][24].…”
Section: Introductionmentioning
confidence: 99%