2017
DOI: 10.1002/hed.24879
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Symptom burden as a driver of decisional regret in long‐term oropharyngeal carcinoma survivors

Abstract: OPC survivors provide a robust description of their long-term outcomes with 15.5% expressing "moderate to high" regret that was significantly associated with late symptom burden and multimodality treatment. Difficulty swallowing was the strongest driver of decisional regret.

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Cited by 52 publications
(88 citation statements)
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References 33 publications
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“…Furthermore, no differences in objective swallowing outcome metrics (PAS or MBSImP©) were observed between participants who were tube dependent and those consuming an oral diet. Indeed, these findings support the recommendations for a systematic approach of dysphagia surveillance throughout survivorship that incorporates instrumental assessment along with patient‐reported outcome measures to interpret a patient's functional swallowing ability …”
Section: Discussionsupporting
confidence: 71%
“…Furthermore, no differences in objective swallowing outcome metrics (PAS or MBSImP©) were observed between participants who were tube dependent and those consuming an oral diet. Indeed, these findings support the recommendations for a systematic approach of dysphagia surveillance throughout survivorship that incorporates instrumental assessment along with patient‐reported outcome measures to interpret a patient's functional swallowing ability …”
Section: Discussionsupporting
confidence: 71%
“…It is not possible to know whether this reflects greater numbers of survivors affected by dysphagia, or greater reporting or coding of this outcome with growing awareness in the clinical community. Nonetheless, the persistently high prevalence of dysphagia at the population level in modern survivors is noteworthy as swallowing difficulty is a top driver of decisional regret in survivorship and is a leading source of noncancer mortality in survivorship …”
Section: Discussionmentioning
confidence: 99%
“…Dysphagia is a high‐impact morbidity of head and neck cancer (HNC). Swallowing difficulty can result from tumor or treatment and adversely impacts both the health and quality of life of survivors. Prevalence estimates for dysphagia vary widely in published literature and depend on tumor stage, subsite of disease, age, and treatment modality.…”
Section: Introductionmentioning
confidence: 99%
“…1 Swallowing dysfunction, or dysphagia, is an important and potentially chronic complication after RT to the oropharynx and has a demonstrated negative impact on quality of life (QOL). [2][3][4] Moreover, although highly conformal RT techniques have become standard in the treatment of these cancers, demonstrating improved sparing of the parotid salivary glands and more favorable rates of long-term xerostomia, 5 the benefit of conformal treatment with regard to swallowing function is less clear. Therefore, dysphagia is still commonly cited as a limiting factor in the delivery of curative RT for OPC.…”
Section: Introductionmentioning
confidence: 99%