Symptom severity assessment of allergic rhinitis: part 1

Spector, Sheldon L.; Nicklas, Richard A.; Chapman, Jean A.; Bernstein, I. Leonard; Berger, William; Blessing-Moore, Joann; Dykewicz, Mark S.; Fineman, Stanley; Lee, Rufus E.; Li, James T.; Portnoy, Jay M.; Schuller, Diane E.; Lang, David M.; Tilles, Stephen A.

doi:10.1016/s1081-1206(10)62160-6

Cited by 122 publications

(91 citation statements)

References 12 publications

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“…Visual analogue scales are quantitative measures largely validated in many diseases (1401,1402). The scales have been extensively used to assess the severity of rhinitis (728,(1403)(1404)(1405)(1406) as well as the efficacy of therapeutic interventions (118,(1406)(1407)(1408)(1409)(1410). The VAS was proposed by the Joint Task Force on Practice Parameters for the symptom severity assessment of allergic rhinitis (118).…”

Section: Assessment Of the Severity And Control Of Rhinitismentioning

confidence: 99%

“…The scales have been extensively used to assess the severity of rhinitis (728,(1403)(1404)(1405)(1406) as well as the efficacy of therapeutic interventions (118,(1406)(1407)(1408)(1409)(1410). The VAS was proposed by the Joint Task Force on Practice Parameters for the symptom severity assessment of allergic rhinitis (118). This Task Force proposed to use several VAS to account for the different symptoms of allergic rhinitis because some, such as nasal congestion, may be more relevant to rhinitis severity (1117).…”

Section: Assessment Of the Severity And Control Of Rhinitismentioning

confidence: 99%

See 1 more Smart Citation

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Bousquet¹,

Khaltaev²,

Cruz³

et al. 2008

Allergy

3,867

1,761

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Section: Assessment Of the Severity And Control Of Rhinitismentioning

confidence: 99%

Section: Assessment Of the Severity And Control Of Rhinitismentioning

confidence: 99%

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Bousquet¹,

Khaltaev²,

Cruz³

et al. 2008

Allergy

3,867

1,761

View full text Add to dashboard Cite

“…However, there is no doubt that the recurrence rate of polyps in allergic individuals is greater than is that observed in non-allergic individuals. (55) …”

Section: Comorbiditiesmentioning

confidence: 99%

Rinite alérgica: indicadores de qualidade de vida

Camelo-Nunes

Solé

2010

J. bras. pneumol.

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The objective of this review was to present evidence of the relationship between allergic rhinitis and impairment of quality of life. The data sources were original articles, reviews and consensus statements entered into the Medline and LILACS databases between 1997 and 2008. The following search terms were used: "allergic rhinitis"; "quality of life"; and "sleep disorders". Quality of life is often impaired in patients with allergic rhinitis, due to the classic symptoms of the disease (sneezing, pruritus, rhinorrhea and nasal obstruction). In addition, the pathophysiology of allergic rhinitis often disrupts sleep, leading to fatigue, irritability, memory deficits, daytime sleepiness and depression. The total burden of this disease goes beyond impairment of physical and social functioning. It has also a financial impact, which becomes greater when we consider the evidence that allergic rhinitis is a possible causal factor of comorbidities, such as asthma and sinusitis. Nasal obstruction, the most prominent symptom, is associated with sleep disorders, which can have a profound effect on mental health, learning, behavior and attention. Finally, allergic rhinitis-a chronic condition that affects adults, adolescents and children-is often underdiagnosed or inadequately treated. The deleterious impact that allergic rhinitis-related sleep disorders have on patient capacity to perform activities of daily living is an important component of the morbidity of the disease. With an accurate diagnosis, there are various available treatments that can reduce the burden of allergic rhinitis.Keywords: Rhinitis, allergic, perennial; Rhinitis, allergic, seasonal; Quality of life; Sleep disorders. ResumoO objetivo desta revisão foi apresentar evidências da relação entre rinite alérgica e redução da qualidade de vida. As fontes de dados foram artigos originais, revisões e consensos indexados nos bancos de dados Medline e LILACS entre 1997 e 2008. As palavras de busca foram "rinite alérgica", "qualidade de vida" e "distúrbios do sono". Os pacientes com rinite alérgica frequentemente têm redução na qualidade de vida causada pelos sintomas clássicos da doença (espirros, prurido, coriza e obstrução). Além disso, a fisiopatologia da rinite alérgica, com frequência, interrompe o sono, ocasionando fadiga, irritabilidade, déficits de memória, sonolência diurna e depressão. A carga total da doença recai não apenas no funcionamento social e físico prejudicados, mas também no impacto financeiro, que se torna maior quando se consideram as evidências de que a rinite alérgica é um possível fator casual de comorbidades, tais como a asma e a sinusite. A obstrução nasal, o mais proeminente dos sintomas, está associada a eventos respiratórios relacionados aos distúrbios do sono, uma condição que tem profundo efeito sobre a saúde mental, o aprendizado, o comportamento e a atenção. Finalmente, a rinite alérgica -doença crônica que afeta crianças, adolescentes e adultos -frequentemente é subdiagnosticada ou inadequadamente tratada. O impacto dele...

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“…(38), nasal airflow and adverse events frequency. In the original studies, different scoring systems and scales were used to evaluate symptoms (usually a daily assessment of symptoms recorded on a diary and subsequently summarized and averaged).…”

Section: Data Synthesismentioning

confidence: 99%

Efficacy of mometasone furoate nasal spray in the treatment of allergic rhinitis. Meta‐analysis of randomized, double‐blind, placebo‐controlled, clinical trials

Penagos

Compalati

Tarantini

et al. 2008

Allergy

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Rationale: Several randomized, double‐blind, placebo‐controlled clinical trials have demonstrated the efficacy of mometasone furoate nasal spray (MFNS) in the treatment of allergic rhinitis (AR) thus allowing for a meta‐analysis to determine the overall treatment effect.Methods: A comprehensive search of the MEDLINE, LILACS, SCOPUS, and the Cochrane Library databases up to 31 October, 2007 was carried out. Randomized, double‐blind, placebo‐controlled, clinical trials evaluating the efficacy of MFNS in patients with AR compared to placebo were included. Total nasal symptom scores (TNSS), individual nasal symptoms, total non‐nasal symptom scores (TNNSS) and nasal airflow were analysed as the standardized mean difference (SMD). Meta‐analysis was performed with the random or the fixed effect models depending on heterogeneity, by using revman 5 software.Data synthesis: Sixteen of the 113 identified articles met the inclusion criteria. For MFNS efficacy on TNSS, 2998 participants were analysed: 1534 received MFNS and 1464 placebo. Mometasone furoate nasal spray was associated with a significant reduction in TNSS (SMD −0.49, 95% CI: −0.60 to −0.38; P < 0.00001; I2 = 50.1%). A significant effect on SMD for nasal stuffiness/congestion (−0.41; 95% CI: −0.56 to −0.27), rhinorrhoea (−0.44; 95% CI: −0.66 to −0.21), sneezing (−0.40; 95% CI: −0.57 to −0.23) and nasal itching (−0.39; 95% CI: −0.53 to −0.25) was also demonstrated. Mometasone furoate nasal spray treated subjects also showed a significant reduction in TNNSS (−0.30; 95% CI: −0.43 to −0.18). The proportion of patients with adverse events was similar for MFNS and placebo (0.99; 95% CI: 0.81–1.20; P = 0.91).Conclusions: This meta‐analysis provides a level Ia evidence for the efficacy of MFSN in the treatment of AR vs placebo. Adverse events frequency was similar in both groups.

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Symptom severity assessment of allergic rhinitis: part 1

Cited by 122 publications

References 12 publications

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Rinite alérgica: indicadores de qualidade de vida

Efficacy of mometasone furoate nasal spray in the treatment of allergic rhinitis. Meta‐analysis of randomized, double‐blind, placebo‐controlled, clinical trials

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