Myzus persicae (Sulzer) is one of major insect pests which infest many vegetable crops especially potato plants. Some natural materials such as, neem oil, menthol oil and nano chitosan were used in controlling M. persicae. The results showed that, neem oil was the most effective compound in controlling M. persicae with LC 50 63.60 ppm, followed by menthol oil then nano chitosan with LC 50 100.26 and 101.62 ppm, respectively.