1973
DOI: 10.1136/jnnp.36.6.1034
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Symptomatic sarcoidosis of skeletal muscle

Abstract: SUMMARY Two patients with chronic sarcoid myopathy are described. Both were middle-aged females and both showed the features of pseudohypertrophy. In other aspects they contrasted markedly. In one (A.R.) the sheer volume of granuloma and its effect on muscle fibres was sufficient to explain the muscle weakness and electromyography confirmed a pure myopathy. In the other (J.W.) the muscle granuloma was sparsely distributed and an associated neuropathy contributed importantly to the disability. There was no clin… Show more

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Cited by 71 publications
(41 citation statements)
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“…Creatine phosphokinase (CPK) is normal. The second type is nodular sarcoid myositis, 3,9 as seen in our case. Painful, growing nodules usually occur in muscles of the extremities, and the lesion might be confused with soft tissue tumors.…”
Section: Skeletal Muscle Involvement Is Part Of the Clinicalmentioning
confidence: 49%
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“…Creatine phosphokinase (CPK) is normal. The second type is nodular sarcoid myositis, 3,9 as seen in our case. Painful, growing nodules usually occur in muscles of the extremities, and the lesion might be confused with soft tissue tumors.…”
Section: Skeletal Muscle Involvement Is Part Of the Clinicalmentioning
confidence: 49%
“…13 The least frequent type of sarcoid muscle disease is acute sarcoid myositis. 3,4,8 In this type the patients are relatively young, with rapidly progressive myopathy mimicking acute dermatomyositis. The symptoms include fever, myalgia and proximal weakness, with an increased CPK level, which indicates muscle damage.…”
Section: Skeletal Muscle Involvement Is Part Of the Clinicalmentioning
confidence: 99%
See 1 more Smart Citation
“…Muscular involvement is usually asymptomatic [ 15]; symptomatic involvement of muscle occurs with considerably less frequency [6]. There are three main clinical types of sarcoidosis with symptomatic involvement of muscles [6,16]: type I, the palpable nodular type, which is the least common although it was the form first reported by Licharew; type 1I, the acute myositic type, which occurs in the early stage of sarcoidosis, in which inflammatory process may cause myalgia and muscular tenderness; and type III, the chronic myopathic type, in which patients may present with weakness and wasting of the muscles. In this study, the lesions in case 1 and case 2 were compatible with type I, and case 3 was type II.…”
Section: Discussionmentioning
confidence: 99%
“…There are four types of muscular sarcoidosis: nodular, chronic myopathy, acute myositis, and asymptomatic. 3,6,7 The acute myositic type occurs in the early stage of sarcoidosis, in which the inflammatory process causes myalgia. Magnetic resonance imaging (MRI) is unusually negative due to small size of lesions.…”
Section: Introductionmentioning
confidence: 99%