Symptoms, menopause status, and country differences

Obermeyer, Carla Makhlouf; Reher, David; Saliba, Matilda

doi:10.1097/gme.0b013e318046eb4a

Cited by 165 publications

(65 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…W orldwide, hot flashes are among the most commonly reported symptoms among women transitioning through menopause, [1][2][3][4][5][6] and in certain populations, hot flashes affect up to 75% of women undergoing this transition. 1 Both the perimenopausal and postmenopausal stages of the transition are characterized by hot flashes, with perimenopause lasting 5-10 years 7,8 in some populations.…”

Section: Introductionmentioning

confidence: 99%

“…Ameliorating the effect of hot flashes on daily life is important because hot flashes are associated with a decrease in quality of life and are the most common reason for seeking medical intervention during the menopausal transition. 1,7,10 To date, few risk factors for hot flashes have been identified; those that have been identified include black race, [11][12][13] obesity, [13][14][15][16][17] cigarette smoking, 3,4,[12][13][14][15][16][17][18][19] and alcohol consumption. 13,16,20,21 The relationship between hot flashes and certain reproductive history variables, including age at menarche, age at first and last pregnancy, and parity, is less clear.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Reproductive History and Hot Flashes in Perimenopausal Women

Nakano

Pinnow

Flaws

et al. 2012

Journal of Women's Health

View full text Add to dashboard Cite

Background: Hot flashes affect up to 75% of women undergoing the menopausal transition. They are among the most common health problems for perimenopausal women and are associated with a decrease in quality of life. The goal of this study was to examine the associations between reproductive history variables and midlife hot flashes. Methods: Data were analyzed from 388 perimenopausal women who participated in the Midlife Health Study, a population-based, cross-sectional study of 639 women aged 45-54 years living in the Baltimore metropolitan region. Results: The unadjusted analyses showed that none of the reproductive history variables analyzed, including age at menarche, number of live births, ever having been pregnant, age at first birth, age at last pregnancy, and history of oral contraceptive use, were associated with ever experiencing hot flashes. However, after adjusting for race, age group, marital status, education, employment, total family income, smoking and alcohol status, and body mass index (BMI), age at last pregnancy was significantly associated with moderate to severe hot flashes. Specifically, participants who were ‡ 36 years of age at last pregnancy were less likely to report moderate or severe hot flashes than those £ 35 years of age at last pregnancy (odds ratio 0.36, 95% confidence interval 0.16, 0.84). Conclusions: In this study, in general, characteristics of reproductive history were not associated with midlife hot flashes. However, there are a number of potentially modifiable factors that are associated with the occurrence of hot flashes. Thus, alternatives may be available when hormone treatment is contraindicated.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Reproductive History and Hot Flashes in Perimenopausal Women

Nakano

Pinnow

Flaws

et al. 2012

Journal of Women's Health

View full text Add to dashboard Cite

show abstract

“…The size of our cohort allowed us to analyze specifically women who experienced menopause during follow-up, resulting in a restriction of our population, but diminishing the potential for a recall bias without creating any selection bias, and concentrating our analysis on critical periods. Most previous studies focused on the prevalence of menopausal symptoms [2][3][4][5][6]8,9,12], which reflects both their onset and their duration in an indistinguishable manner. Moreover, previous studies on menopausal symptoms either included or excluded women on HRT [3,7].…”

Section: Discussionmentioning

confidence: 99%

“…These may occur before or after the onset of menopause. Studies on the prevalence of menopausal symptoms during menopausal transition have reported that these were more likely to be experienced in late menopausal transition and in early postmenopause [2][3][4][5][6][7][8][9][10][11][12]. However, the main methodologic issues that limit inferences from epidemiologic studies of the menopausal transition are lack of longitudinal studies and short follow-up [5,13].…”

Section: Introductionmentioning

confidence: 99%

“…However, the main methodologic issues that limit inferences from epidemiologic studies of the menopausal transition are lack of longitudinal studies and short follow-up [5,13]. Another limitation is that few studies include surgical menopause cases [2,4,14]. Moreover, later age at menopause was associated with a decrease in the risk of occurrence of hot flushes and vaginal dryness in some studies [14,15], but it remains unclear whether the onset of menopausal symptoms varies across different time periods of menopausal transition according to age at menopause.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Risk of onset of menopausal symptoms in periods surrounding menopause

et al. 2007

View full text Add to dashboard Cite

To cite this version:Séverine Sabia, Agnès Fournier, Sylvie Mesrine, Marie-Christine Boutron-Ruault, Françoise ClavelChapelon. Risk of onset of menopausal symptoms in periods surrounding menopause.. Maturitas, Elsevier, 2007, 58 (4) AbstractObjective: To assess the risk of onset of menopausal symptoms at different periods surrounding menopause, and variations in this risk according to age at menopause and type of menopause. Methods: We analyzed the 27,897 women participating in the French E3N cohort study who reached menopause during a 10-year follow-up period (1990)(1991)(1992)(1993)(1994)(1995)(1996)(1997)(1998)(1999)(2000). Self-administered questionnaires, completed approximately every 24 months, included questions on the use of hormonal treatments, reproductive factors, personal history of a variety of diseases and the occurrence of personal medical events, including menopausal symptoms. Hazard ratios (HRs) were computed from multivariate Cox models. Results: When compared to the year preceding menopause, the risk of onset of menopausal symptoms was higher in the year following menopause (for natural menopause (n = 25,753), HR= 1.22, 95% confidence interval: 1.17, 1.27, and for artificial menopause (n = 2,147), HR= 2.21, 95% CI: 1.93, 2.52). More than one year prior to menopause and more than one year after, HRs were significantly below unity. The risk of onset of menopausal symptoms in the year following menopause was 1.47-fold (95% CI: 1.31, 1.64) higher in women having undergone an artificial menopause than in women who had had a natural menopause. In other periods, the risks did not differ significantly according to type of menopause. Those who experienced menopausal symptoms in the 1-5 year period following menopause were more likely to have reached their menopause before 51 years. Conclusions:The risk of onset of menopausal symptoms at different time periods surrounding menopause varies according to both type of menopause and age at menopause.

show abstract

Menopause (evolution)

Sievert

2015

The International Encyclopedia of Human Sexuality

View full text Add to dashboard Cite

Menopause is the cessation of menstruation due to the loss of ovarian follicular activity. It is a visible marker of the end of fertility. Within a biomedical framework, the menopausal transition is often associated with sexual difficulties, such as a loss of interest in sex and vaginal dryness; however, some women report an increase in sexual desire and activity after menopause because of freedom from concerns about pregnancy. From an evolutionary perspective, there is little selective advantage in maintaining sexual desire and sexual function after menopause beyond the benefits of maintaining a pair bond to provide extra resources for the final offspring.

show abstract

Symptoms, menopause status, and country differences

Abstract: Similarities among core symptoms and differences in the expression of symptoms were found across sites. Both biological (menopause status) and cultural (country of residence) variables influence symptomatology.

Cited by 165 publications

References 35 publications

Reproductive History and Hot Flashes in Perimenopausal Women

Reproductive History and Hot Flashes in Perimenopausal Women

Risk of onset of menopausal symptoms in periods surrounding menopause

Menopause (evolution)

Contact Info

Product

Resources

About