Symptoms of discoid lateral menisci

Mutlu, Serhat; Mutlu, Harun; Mutlu, Burcu; Güler, Olcay; Duymuş, Tahir Mutlu

doi:10.1016/j.jor.2014.06.005

Cited by 10 publications

(8 citation statements)

References 14 publications

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“…Most patients exhibited one to three symptoms. The two most common symptoms were pain, and popping and snapping, which were similar to other studies [ 13 , 19 , 20 ]. Male patients showed a higher incidence of popping and snapping, while women manifested a higher ROM limitation.…”

Section: Discussionsupporting

confidence: 90%

Symptomatic discoid lateral meniscus: a clinical and arthroscopic study in a Chinese population

Chen

Zhong

2016

BMC Musculoskelet Disord

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BackgroundDiscoid lateral meniscus (DLM) is relatively common in East Asia..Symptomatic discoid lateral meniscus (SDLM) is an important indication for knee arthroscopic surgery. However, studies investigating SDLM are rare. The purpose of this study was to evaluate the clinical characteristics and intra-articular variants of SDLM in a Chinese population.MethodsWe retrospectively reviewed all patients with SDLM from January 2005 to December 2014 in our hospital. Clinical variables included gender, age, duration, age of onset, affected side, symptoms and trauma history as well as arthroscopic findings: DLM types, tear patterns and concomitant medial meniscus tear, which were evaluated and compared statistically.ResultsOf the 496 consecutive participants with SDLM, females outnumbered males (69.6 % vs. 30.4 %). The age of onset ranged from 3 to 80 years (median, 31 years), and was significantly higher in females than in males (p < 0.0001). Trauma history in males was significantly higher than in females (45 % vs. 35.1 %, p = 0.0356). Males showed a higher incidence of popping and snapping, while females manifested higher range-of-motion (ROM) limitations (p = 0.0179, and p = 0.0392, respectively). No significant difference in intra-articular variants was observed between genders. The complete type was the most frequent (344, 69.4 %), followed by the incomplete type (149, 30 %), and the Wrisberg type (3, 0.6 %). Significant difference in tear patterns was found between complete and incomplete types (p < 0.0001). Few patients showed medial meniscus tear (11, 2.2 %), at a significantly higher age compared with patients without tear (median, 57 years vs. 33 years, p < 0.0001).ConclusionsThe majority of Chinese patients with SDLM are young and middle-aged females. Female patients had an older age of onset, higher incidence of ROM limitation and limited trauma history. The complete type is the most common, with tear patterns varying between complete and incomplete types. The SDLM does not significantly affect the medial meniscus.

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Section: Discussionsupporting

confidence: 90%

Symptomatic discoid lateral meniscus: a clinical and arthroscopic study in a Chinese population

Chen

Zhong

2016

BMC Musculoskelet Disord

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“…However, a click or pain can develop even in the absence of a tear or instability33). Symptoms of discoid meniscus include insidious popping or snapping without a traumatic origin, which is associated with pain, giving way, effusion, quadriceps atrophy, limited range of motion, and clicking or locking28,34). Snapping knee syndrome, in which a clunk is heard at the end of flexion, is usually related to an unstable meniscus variant, such as the Wrisberg type35,36).…”

Section: Clinical Featuresmentioning

confidence: 99%

Diagnosis and Treatment of Discoid Meniscus

Kim

Han

Lee

2016

Knee Surg Relat Res

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There is a greater incidence of discoid meniscus in Asian countries than in Western countries, and bilateral discoid menisci are also common. The discoid meniscus may be a congenital anomaly, and genetics or family history may play a role in the development of discoid menisci. Because the histology of discoid meniscus is different from that of normal meniscus, it is prone to tearing. Individuals with a discoid meniscus can be asymptomatic or symptomatic. Asymptomatic discoid menisci do not require treatment. However, operative treatment is necessary if there are symptoms. Total meniscectomy leads to an increased risk of osteoarthritis. Therefore, total meniscectomy is generally reserved for rare unsalvageable cases. Partial meniscectomy (saucerization) with preservation of a stable peripheral rim combined with or without peripheral repair is effective, and good short-, mid-, and long-term clinical results have been reported.

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“…When successful, analysis has relied upon an assortment of 1 and 2D NMR spectroscopy together with sophisticated mass spectrometry techniques. 3 Molecular sequencing techniques such as Edman degradation for peptides and Sanger sequencing for DNA are among the most significant chemical achievements of the 20th century. Modern proteomic studies rely on comparisons to databases for protein identification, 4 wherein many of the protein sequences were elucidated via Edman degradations.…”

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confidence: 99%

Sequencing of Sequence-Defined Oligourethanes via Controlled Self-Immolation

et al. 2020

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Sequence-defined polymers show promise for biomimetics, self-assembly, catalysis, and information storage, wherein the primary structure begets complex chemical processes. Here we report the solution-phase and the high-yielding solid-phase syntheses of discrete oligourethanes and methods for their self-immolative sequencing, resulting in rapid and robust characterization of this class of oligomers and polymers, without the use of MS/MS. Crucial to the sequencing is the inherent reactivity of the terminal alcohol to "unzip" the oligomers, in a controlled and iterative fashion, releasing each monomer as a 2-oxazolidinone. By monitoring the self-immolation reaction via LC/MS, an applied algorithm rapidly produces the sequence of the oligourethane. Not only does this process provide characterization of structurally complex molecules, it works as a reader of molecular information.Sequence-defined polymers, e.g., β-peptides, γ-peptides, peptoids, polyureas, and polycarbamates, 1 have garnered significant interest over recent decades, to the point that their size and structural complexity are nearing those of biopolymers. 2 This complexity renders sequence elucidation difficult, at times -impossible. When successful, analysis has relied upon an assortment of 1 and 2D NMR spectroscopy together with sophisticated mass spectrometry techniques. 3 Molecular sequencing techniques such as Edman degradation for peptides and Sanger sequencing for DNA are among the most significant chemical achievements of the 20th century. Modern proteomic studies rely on comparisons to databases for protein identification, 4 wherein many of the protein sequences were elucidated via Edman degradations. Notably, very few techniques analogous to Edman or Sanger sequencing exist for synthetic macromolecules, likely due to the fact that only recently has synthetic methodology been capable of creating monodisperse macromolecules as structurally complex as biopolymers. 1 Peptoids are one exception, with Zuckerman realizing their stepwise chemical degradation on resin. 5 As more examples of sequence-defined

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Symptoms of discoid lateral menisci

Cited by 10 publications

References 14 publications

Symptomatic discoid lateral meniscus: a clinical and arthroscopic study in a Chinese population

Symptomatic discoid lateral meniscus: a clinical and arthroscopic study in a Chinese population

Diagnosis and Treatment of Discoid Meniscus

Sequencing of Sequence-Defined Oligourethanes via Controlled Self-Immolation

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