“…The early emergence of CR cells underlies their histogenetic influence on later-born neurons (Ogawa et al, 1995;de Frutos et al, 2016), which is assisted by their tangential dispersion (Bielle et al, 2005;Barber et al, 2015). By contrast, the majority of subplate (SP) neurons, another developmentally influential type of early-born neurons Ghosh et al, 1990;Ohtaka-Maruyama et al, 2018;reviewed in Allendoerfer and Shatz, 1994;Hoerder-Suabedissen and Molnár, 2015), are thought not to migrate tangentially from their origins in the dorsal pallium (reviewed in Barber and Pierani, 2016). However, 3 recent studies have shown that SP neurons come from an extracortical (rostromedial) origin via a medial-to-lateral influx (Pedraza et al, 2014;García-Moreno et al, 2018), and that a fraction of neurons born in the ventricular zone (VZ) of the pallium and PS interface migrate ventrally to contribute to the olfactory cortex, amygdala, striatum, or other forebrain structures (Tomioka et al, 2000;Hamasaki et al, 2001;Hirata et al, 2002;García-Moreno et al, 2008;Cocas et al, 2009;Pombero et al, 2011).…”