Syndrome Of Inappropriate Antidiuretic Hormone

Chastain, C.B.

doi:10.1016/b978-1-4557-0306-7.00068-4

Cited by 3 publications

(10 citation statements)

References 8 publications

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“…The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is defined as an excess of antidiuretic hormone (ADH) in the absence of hypovolemia or hyperosmolality 1 . ADH, or vasopressin, is synthesized in the hypothalamus and transported down the pituitary stalk, where it is stored in the pars nervosa of the posterior pituitary gland 2 .…”

Section: Introductionmentioning

confidence: 99%

“…ADH, or vasopressin, is synthesized in the hypothalamus and transported down the pituitary stalk, where it is stored in the pars nervosa of the posterior pituitary gland 2 . ADH is normally secreted when there is an increase in plasma osmolality, decrease in blood pressure, or decrease in circulating blood volume 1 . Once released, ADH binds to the V2 receptors on the basolateral membrane of the cells in the collecting ducts of the kidneys and promotes the resorption of water back into circulation via the insertion of aquaporin channels 3 .…”

Section: Introductionmentioning

confidence: 99%

“…In cases of SIADH, ADH is secreted autonomously, unrelated to changes in blood volume or osmolality. An excess of ADH results in hyponatremia, hypoosmolality, increased urine osmolality, and increased urinary sodium 1 . This syndrome produces a dilutional hyponatremia because only water, and not sodium, is retained.…”

Section: Introductionmentioning

confidence: 99%

“…This syndrome produces a dilutional hyponatremia because only water, and not sodium, is retained. The increase in plasma volume secondary to the water retention suppresses the release of aldosterone and produces an increased glomerular filtration rate, stimulating an increase in sodium excretion 1 . Most cases of hyponatremia in hospitalized human patients spontaneously resolve; however, this electrolyte abnormality is associated with longer hospital stays and higher mortality rates 4 …”

Section: Introductionmentioning

confidence: 99%

“…In human medicine, SIADH has been associated with cerebral disorders, including head trauma, pulmonary disease, the administration of a variety of medications, and other physiological changes such as pain, nausea, and stress 1 . The mechanisms by which SIADH occurs are largely unknown 1 .…”

Section: Introductionmentioning

confidence: 99%

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Syndrome of inappropriate antidiuretic hormone secretion secondary to trauma in a dog

Cilli

Bellis

2021

J Vet Emergen Crit Care

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Objective To describe a case of inappropriate antidiuretic hormone (ADH) secretion in a dog secondary to trauma. Case Summary A 14‐year‐old neutered female mixed breed dog presented for evaluation of bite wounds. The dog sustained multiple puncture wounds to the cervical area, stifle, and elbow. Treatment was initiated with isotonic crystalloid fluids, analgesia, broad‐spectrum antimicrobials, and gastroprotectants. The dog developed hyponatremia with concurrent serum hypoosmolality and inappropriate urine hyperosmolality and urine sodium secretion, leading to a diagnosis of the syndrome of inappropriate ADH secretion. The hyponatremia improved, and the dog improved clinically and was discharged 3 days after admission. New or Unique Information Provided This is the first case description of the syndrome of inappropriate ADH secretion in a dog suffering from trauma. Inappropriate ADH secretion is largely under‐recognized in veterinary patients. Increased awareness of this syndrome can lead to initiation of appropriate treatment and improved outcomes.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Syndrome of inappropriate antidiuretic hormone secretion secondary to trauma in a dog

Cilli

Bellis

2021

J Vet Emergen Crit Care

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Suspected paraneoplastic syndrome of inappropriate antidiuretic hormone secretion associated with a gastric adenocarcinoma in a dog

Thomas,

Finlay,

Sharp

2024

Aust Veterinary J

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This report describes a suspected case of paraneoplastic syndrome of inappropriate antidiuretic hormone (SIADH) in a 5‐year‐old male entire Australian Kelpie associated with a gastric adenocarcinoma. The dog had a history of chronic vomiting and presented with hyponatraemia, hypokalaemia, hypochloraemia and increased urinary sodium. Computed tomography identified the presence of a gastric tumour and histopathology confirmed a pyloric gastric adenocarcinoma. Removal of the tumour via a Billroth I procedure resulted in rapid resolution of electrolyte derangements. The dog was still alive six months postoperatively with no recurrence of either SIADH or tumour at the time of publication.

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Nursing strategies for the mechanically ventilated patient

Meitner,

Feuerstein,

Steele

2023

Front. Vet. Sci.

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The goal of this manuscript is to provide a comprehensive and multi-disciplinary review of the best nursing practices of caring for mechanically ventilated patients. By reviewing human medicine literature, the authors will extrapolate procedures that have been found to be most effective in reducing the risk of mechanical ventilation (MV) complications. Paired with review of the current standards in veterinary medicine, the authors will compile the best practice information on mechanically ventilated patient care, which will serve as a detailed resource for the veterinary nursing staff. Written from a nursing standpoint, this manuscript aims to consolidate the nursing assessment of a mechanically ventilated patient, addressing both systemic and physical changes that may be encountered during hospitalization. The goal of this review article is to present information that encourages a proactive approach to nursing care by focusing on understanding the effects of polypharmacy, hemodynamic changes associated with MV, complications of recumbent patient care, and sources of hospital acquired infections. When applied in conjunction with the more technical aspects of MV, this manuscript will allow veterinary technicians involved in these cases to understand the dynamic challenges that mechanically ventilated patients present, provide guidance to mitigate risk, address issues quickly and effectively, and create an up-to date standard of practice that can be implemented.

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Syndrome Of Inappropriate Antidiuretic Hormone

Cited by 3 publications

References 8 publications

Syndrome of inappropriate antidiuretic hormone secretion secondary to trauma in a dog

Syndrome of inappropriate antidiuretic hormone secretion secondary to trauma in a dog

Suspected paraneoplastic syndrome of inappropriate antidiuretic hormone secretion associated with a gastric adenocarcinoma in a dog

Nursing strategies for the mechanically ventilated patient

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