Syndrome of pleural and retrosternal "bridging" fibrosis and retroperitoneal fibrosis in patients with asbestos exposure

Cottin, Vincent; Brillet, Pierre-Yves; Combarnous, François; Duperron, F.; Nunès, Hilario; Cordier, J.-F.

doi:10.1136/thx.200x.081646

Cited by 16 publications

(9 citation statements)

References 13 publications

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“…Several factors such as medication (β-blocker, hydralazine or methylsergide), surgery, radiation, infections, and exposure to asbestos have been described as predisposing factors for developing RPF, despite a scarcity of data to establish a clear causal relationship (2, 5, 20). In our study, many patients had cardiovascular risk factor such as hypertension, dyslipidemia, and tobacco exposure, and 18% of patients already had a cerebrovascular disease.…”

Section: Discussionmentioning

confidence: 99%

Retroperitoneal Fibrosis in 27 Korean Patients: Single Center Experience

Jung

Lee

et al. 2011

J Korean Med Sci

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Retroperitoneal fibrosis (RPF) is a rare disease with unclear etiology, which is characterized by chronic non-specific inflammation of the retroperitoneum. This study was performed to investigate the clinical characteristics, laboratory findings, radiologic findings, treatment and outcome in Korean patients with RPF. We retrospectively reviewed medical records of 27 RPF patients who were admitted to Yonsei University Medical Center between 1998 and 2009. Twenty-two patients (81%) were male. The mean age at diagnosis was 56 yr. Nine patients had identifiable risk factors of RPF and three patients had combined autoimmune diseases. Acute phase reactants were elevated in most patients. Rheumatoid factor was positive in 3 of 16 patients (19%) and antinuclear antibody in 4 of 17 (24%). Five of 6 patients who were taken positron-emission tomography showed positive uptake. Glucocorticoids were used in 16 patients (59%) and four of them received combination therapy with azathioprine. After immunosuppressive treatment, the levels of acute phase reactants dropped, and the size of mass also decreased in most patients. In conclusion, the clinical characteristics of RPF in Korean patients are similar with other series except for higher proportion of male. Some patients with RPF have autoimmune features. The effect of immunosuppressive treatment on RPF is good.

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Section: Discussionmentioning

confidence: 99%

Retroperitoneal Fibrosis in 27 Korean Patients: Single Center Experience

Jung

Lee

et al. 2011

J Korean Med Sci

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“…In our experience, such changes are rarely found even in asbestos-exposed persons having other marked pleural pathology. Two similar cases having slight asbestos exposure and no other known risk factors for RPF have been recently reported in France [ 16 ]. It seems that asbestos can induce unusually severe fibrotic reaction in some susceptible individuals.…”

Section: Discussionmentioning

confidence: 81%

“…To our knowledge, the literature contains only three reports describing asbestos-related pleural findings in altogether five RPF patients [ 14 - 16 ]. In our study 16 out of 22 (73%) asbestos-exposed RPF patients had asbestos-related pleural pathology in their chest HRCT.…”

Section: Discussionmentioning

confidence: 99%

Asbestos-related pleural and lung fibrosis in patients with retroperitoneal fibrosis

Uibu

Järvenpää

Hakomäki

et al. 2008

Orphanet J Rare Dis

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Background: Retroperitoneal fibrosis (RPF) is a rare fibroinflammatory disease that leads to hydronephrosis and renal failure. In a case-control study, we have recently shown that asbestos exposure was the most important risk factor for RPF in the Finnish population. The aim of this study was to evaluate the relation of asbestos exposure to radiologically confirmed lung and pleural fibrosis among patients with RPF.

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“…“Unknown” or “various” exposures indicate the data came from occupational exposure matrices, including textiles, insulation, or cement workers. Sources: a Olsson, 2004. b Gold, 2007. c Greaves, 1979. d Noonan, 2006. e Pfau, 2008. f Gold, 2007; Noonan, 2006. g Rihova, 2005; Inoue, 2004. h Stratta, 2001. i Rihova, 2005. j Inoue, 2004. k Turner-Warwick, 1970. l Zerva, 1989. m Pfau, 2005; Nigam, 1993; Tamura, 1993; Stansfield, 1974. n Pelclova, 2003. o Pfau, 2005. p Pernis, 1965; Turner-Warwick, 1970; Stansfield, 1974; Lange, 1974. q Zone, 1985; Zerva, 1989. r White, 1974. s van Bommel, 2009; Vaglio, 2009; Uibu, 2004; Sauni, 1998; Maguire, 1991. t Cottin, 2008.…”

Section: Autoimmune Effects Of Asbestosmentioning

confidence: 99%

Nonpulmonary Outcomes of Asbestos Exposure

Bunderson-Schelvan

Pfau

Crouch

et al. 2011

Journal of Toxicology and Environmental Health, Part B

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The adverse pulmonary effects of asbestos are well accepted in scientific circles. However, the extrapulmonary consequences of asbestos exposure are not as clearly defined. In this review the potential for asbestos to produce diseases of the peritoneum, immune, gastrointestinal (GIT), and reproductive systems are explored as evidenced in published, peer-reviewed literature. Several hundred epidemiological, in vivo, and in vitro publications analyzing the extrapulmonary effects of asbestos were used as sources to arrive at the conclusions and to establish areas needing further study. In order to be considered, each study had to monitor extrapulmonary outcomes following exposure to asbestos. The literature supports a strong association between asbestos exposure and peritoneal neoplasms. Correlations between asbestos exposure and immune-related disease are less conclusive; nevertheless, it was concluded from the combined autoimmune studies that there is a possibility for a higher-than-expected risk of systemic autoimmune disease among asbestos-exposed populations. In general, the GIT effects of asbestos exposure appear to be minimal, with the most likely outcome being development of stomach cancer. However, IARC recently concluded the evidence to support asbestos-induced stomach cancer to be “limited.” The strongest evidence for reproductive disease due to asbestos is in regard to ovarian cancer. Unfortunately, effects on fertility and the developing fetus are under-studied. The possibility of other asbestos-induced health effects does exist. These include brain-related tumors, blood disorders due to the mutagenic and hemolytic properties of asbestos, and peritoneal fibrosis. It is clear from the literature that the adverse properties of asbestos are not confined to the pulmonary system.

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Syndrome of pleural and retrosternal "bridging" fibrosis and retroperitoneal fibrosis in patients with asbestos exposure

Cited by 16 publications

References 13 publications

Retroperitoneal Fibrosis in 27 Korean Patients: Single Center Experience

Retroperitoneal Fibrosis in 27 Korean Patients: Single Center Experience

Asbestos-related pleural and lung fibrosis in patients with retroperitoneal fibrosis

Nonpulmonary Outcomes of Asbestos Exposure

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