2010
DOI: 10.1177/1531003511400426
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Syndromes Associated With the Deep Veins: Phlegmasia Cerulea Dolens, May-Thurner Syndrome, and Nutcracker Syndrome

Abstract: Although phlegmasia cerulea dolens, May-Thurner syndrome, and nutcracker syndrome are rare entities, knowledge of these syndromes associated with the deep veins is essential. This study presents current management of these disorders, including diagnostic and interventional strategies. Endovascular techniques have evolved and now play a significant role in the treatment of both phlegmasia cerulea dolens and May-Thurner syndrome. However, endovascular therapy for nutcracker syndrome remains untested.

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Cited by 60 publications
(62 citation statements)
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“…However, that alone is not adequate for the treatment of DVT with May-Thurner, as it fails to address any of the long-term sequelae in this group of pacients. [10] May-Thurner syndrome, in which the overriding right iliac artery compresses the left iliac vein, will rarely respond to conservative treatments, [11] including anticoagulation and fibrinolysis [12], given the physical etiology of the disease. [11] Pacients with iliofemoral thrombosis and May-Thurner should be treated aggressively with catheter directed thrombolysis, percutaneous mechanical trombectomy and angioplasty and stent placement across the common iliac stenosis.…”
Section: Discussionmentioning
confidence: 99%
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“…However, that alone is not adequate for the treatment of DVT with May-Thurner, as it fails to address any of the long-term sequelae in this group of pacients. [10] May-Thurner syndrome, in which the overriding right iliac artery compresses the left iliac vein, will rarely respond to conservative treatments, [11] including anticoagulation and fibrinolysis [12], given the physical etiology of the disease. [11] Pacients with iliofemoral thrombosis and May-Thurner should be treated aggressively with catheter directed thrombolysis, percutaneous mechanical trombectomy and angioplasty and stent placement across the common iliac stenosis.…”
Section: Discussionmentioning
confidence: 99%
“…[13] Operative intervention for May-Thurner with acute thrombosis includes thrombectomy with adjunctive arteriouvenous fistula and relief of the distal iliac obstructionn via dissection of the right common iliac artery off the left common iliac vein. [10] Therefore, early recognition and endovascular treatment of iliac vein compression could prevent a DVT and an improvement in the symptoms. [1] The treatment, however, depends on the presence of DVT.…”
Section: Discussionmentioning
confidence: 99%
“…5,16 In the case of a DVT associated with MTS, systemic anticoagulation alone is not adequate, as it fails to address the underlying anatomical compression. 24,25 It is suggested that the anatomical defect should be repaired with the use of stents and balloon venoplasty. 11 Patients with a high clot burden should also undergo inferior vena cava filter placement.…”
Section: Managementmentioning
confidence: 99%
“…1 Risk factors for PCD include malignancy, immobility, heart failure, heparin-induced thrombocytopenia, prothrombin states (eg, antiphospholipid syndrome), pregnancy, surgery and venous instrumentation (eg, placement of central venous catheters and inferior vena cava filters). 2 Clinically, PCD is characterized by sudden pain, swelling, purple ecchymosis, and arterial ischemia with loss of distal pulses. 3 Edema develops rapidly, and the skin of the affected extremity is usually tense, firm, and tender to palpation.…”
mentioning
confidence: 99%
“…Doppler ultrasound of the affected extremity should be used to confirm the diagnosis of PCD, and initial treatment includes bed rest, elevation of the affected limb, and systemic anticoagulation with heparin. 2 Catheter-directed thrombolysis and venous thrombectomy should also be considered as early treatment options for PCD. 4 v …”
mentioning
confidence: 99%