Synergistic antimicrobial properties of nanoencapsulated clove oil and thymol against oral bacteria

Lee, Ji Soo; Choi, Ye Seul; Lee, Hyeon Gyu

doi:10.1007/s10068-020-00803-w

Cited by 15 publications

(8 citation statements)

References 35 publications

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“…Dental caries and periodontal diseases are initiated by dental plaque (as bacterial communities), with Streptococcus mutans acting as one of the causative agents. To inhibit the growth of the oral pathogenic bacteria, the oral care products containing antiseptics (chlorhexidine, hydrogen peroxide, and triclosan, among others) are highly recommended; nonetheless, some side effects of such actives are a concern, such as teeth discoloration or staining and taste perception [2,3]. The marketing of triclosan in bacterial soaps, for instance, was banned by the Food and Drug Administration, since there was an increasing concern about its presence in the environment and its impacts on the health of beings [4].…”

Section: Introductionmentioning

confidence: 99%

Xylityl Sesquicaprylate Efficacy as an Antiseptic Ingredient for Oral Care Products (Mouthwash): An In Vitro Screening Investigation against Eight Microorganisms

et al. 2022

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For dental caries and periodontal diseases initiated by dental plaque (as bacterial communities) and to inhibit the growth of oral pathogenic bacteria, oral care products containing antiseptic active ingredients are highly recommended, nonetheless, side effects of such actives are a concern (teeth discoloration/staining and taste perception, for example). In this context, we challenged xylityl sesquicaprylate, an antiseptic compound from natural resources, as an active ingredient to be used in an alcohol-free mouthwash formulation. The xylityl sesquicaprylate sample was compared to a respective blank mouthwash formulation and one containing triclosan. The in vitro efficacy was screened by the time-kill assay against eight microorganisms. The xylityl sesquicaprylate-containing mouthwash (0.45% w/w) presented a particularly interesting profile of efficacy against Actinomyces viscosus, Fusobacterium nucleatum, Porphyromonas gingivalis, and Tannerella forsythia, with results of greater magnitude to reduce the log10 of those microorganisms in comparison with the triclosan sample.

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Section: Introductionmentioning

confidence: 99%

Xylityl Sesquicaprylate Efficacy as an Antiseptic Ingredient for Oral Care Products (Mouthwash): An In Vitro Screening Investigation against Eight Microorganisms

et al. 2022

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“…To solve these problems, various studies have been conducted to optimize the extraction process, combine other antimicrobial substances, apply active packaging, and encapsulate antibacterial substances to improve their utilization [18][19][20][21][22].…”

Section: Introductionmentioning

confidence: 99%

Application of Natural Preservatives for Meat and Meat Products against Food-Borne Pathogens and Spoilage Bacteria: A Review

Chin

Paik

2021

Foods

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Meat and meat products are excellent sources of nutrients for humans; however, they also provide a favorable environment for microbial growth. To prevent the microbiological contamination of livestock foods, synthetic preservatives, including nitrites, nitrates, and sorbates, have been widely used in the food industry due to their low cost and strong antibacterial activity. Use of synthetic chemical preservatives is recently being considered by customers due to concerns related to negative health issues. Therefore, the demand for natural substances as food preservatives has increased with the use of plant-derived and animal-derived products, and microbial metabolites. These natural preservatives inhibit the growth of spoilage microorganisms or food-borne pathogens by increasing the permeability of microbial cell membranes, interruption of protein synthesis, and cell metabolism. Natural preservatives can extend the shelf-life and inhibit the growth of microorganisms. However, they can also influence food sensory properties, including the flavor, taste, color, texture, and acceptability of food. To increase the applicability of natural preservatives, a number of strategies, including combinations of different preservatives or food preservation methods, such as active packaging systems and encapsulation, have been explored. This review summarizes the current applications of natural preservatives for meat and meat products.

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“…Chitosan-poly-γ-glutamic acid NPs loaded with clove and thymol essential oils were tested on S. mutans and S. sobrinus strains from human saliva to evaluate their antimicrobial effect. The complex NPs showed synergistic antimicrobial activity against both strains, while the free essential oils combination exhibited additive activity against S. mutans and synergistic activity against S. sobrinus (Lee, Choi & Lee, 2020). Pomegranate (Punica granatum) peel extract loaded in mucoadhesive polyethylenimine-dextran sulphate NPs have also been used to develop a system for halitosis and caries prevention (Tiyaboonchai, Rodleang & Ounaroon, 2015).…”

Section: Oral Bacteria Inhibitionmentioning

confidence: 99%

Enhancement of oral bioavailability of natural compounds and probiotics by mucoadhesive tailored biopolymer-based nanoparticles: A review

Gómez‐Guillén

Montero

2021

Food Hydrocolloids

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Encapsulation in polymer NPs (NPs) is a well-recognized way to improve the oral bioavailability of hydrophobic and hydrophilic compounds by enhancing their solubility in aqueous medium, to protect them from acid and enzymatic degradation in the gastrointestinal tract, and to favour their permeability across the mucosal membranes. Nanostructures rather than larger delivery systems are also proposed to encapsulate prebiotics, probiotics and natural antimicrobial compounds, as they allow greater penetration of the mucous layer, as well as lower and longer the delivery of prebiotics, probiotics and antimicrobials along the gastrointestinal tract. This also includes a previous brief introduction to the complex mucoadhesion mechanism and common evaluation methods for determining mucoadhesiveness in nanoparticulate systems.

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Synergistic antimicrobial properties of nanoencapsulated clove oil and thymol against oral bacteria

Cited by 15 publications

References 35 publications

Xylityl Sesquicaprylate Efficacy as an Antiseptic Ingredient for Oral Care Products (Mouthwash): An In Vitro Screening Investigation against Eight Microorganisms

Xylityl Sesquicaprylate Efficacy as an Antiseptic Ingredient for Oral Care Products (Mouthwash): An In Vitro Screening Investigation against Eight Microorganisms

Application of Natural Preservatives for Meat and Meat Products against Food-Borne Pathogens and Spoilage Bacteria: A Review

Enhancement of oral bioavailability of natural compounds and probiotics by mucoadhesive tailored biopolymer-based nanoparticles: A review

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