Synergistic Effect of a Third Active Glycoside of Senna

Fairbairn, James; Saleh, M. R. I.

doi:10.1038/167988a0

Cited by 6 publications

(3 citation statements)

References 1 publication

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“…These results show that sennoside C is as active as sennoside A and exerts a potentiating effect of about 1.6 when present in a proportion of 20 % of the mixture. This seems to be close to the results given by FAIRBAIRN and SALEH [1]. They have also reported that although the samples of leaf contained a smaller proportion of sennosides expressed as sennoside A A and B than the samples of pod, the former had greater biological activity than the latter.…”

supporting

confidence: 91%

“…In 1951, FAIRBAIRN and SALEH [1] reported that senna leaf and pod contain the "nonrhein" glycoside based on aloe-emodin, which is as active as sennosides A and B, in 10 15 % and 2 5 % of the total glycoside content, respectively. This glycoside exerts a marked synergistic effect increasing the total activity by about 1.7 times when mixed with sennosides A and B so that it represents about 15 % of the mixture; but in proportions of about 5 % it exerts practically no synergistic action.…”

mentioning

confidence: 99%

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Potentiating Effect of Sennoside C on Purgative Activity of Sennoside A in Mice

Kisa¹,

Sasaki²,

Yamauchi³

et al. 1981

Planta Med

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supporting

confidence: 91%

mentioning

confidence: 99%

Potentiating Effect of Sennoside C on Purgative Activity of Sennoside A in Mice

Kisa¹,

Sasaki²,

Yamauchi³

et al. 1981

Planta Med

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“…When the biological activities of senna leaf and fruit extracts were compared, it was seen that they consisted of sennosides A and B, which have high synergistic effects 42 . From the substances in senna seeds, those with slimming effects were determined.…”

Section: Senna Teamentioning

confidence: 99%

Evaluation of the Slimming Effects of Diet Tea in Biochemical and Molecular Meaning

Eyüpoğlu

Arman

2021

Univ J Pharm Res

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The replacement of consumed with foods containing high carbohydrates, fats and proteins exceed that the daily needs of body, causes many health problems, especially obesity. Complicated health problems have been trying to be solved with drugs, but it is not possible to control diseases if obesity is not resolved. Obesity causes inflammation, insulin resistance, vascular endothelial dysfunction, and Low-Density Lipoprotein (LDL) increase. There are very few weight loss drugs with acceptable side effects, and these drugs are not given to people who are not considered obese according to their body mass index. For this reason, people seek the remedy in over the counter (OTC) (mostly products with active ingredients derived from plants) products or herbal teas. These products, which do not have direct effects, have mechanisms that can help and can be supportive with diet and sports. However, these products and teas that cannot be dosed by a knowledgeable healthcare professional can disrupt the balance of the body and cause various diseases. In this study, the effect levels with the mechanisms supporting weight loss on the biochemical parameters of the active substances in the herbal forms sold and consumed as diet tea, were evaluated. Peer Review History: Received: 4 July 2021; Revised: 11 August; Accepted: 6 September, Available online: 15 September 2021 Academic Editor: Dr. Jennifer Audu-Peter, University of Jos, Nigeria, drambia44@gmail.com UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file: Reviewer's Comments: Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 7.5/10 Reviewers: Dr. Gehan Fawzy Abdel Raoof Kandeel, Pharmacognosy Department, National Research Centre, Dokki, 12622, Giza, Egypt, gehankandeel9@yahoo.com Dr. Marwa A. A. Fayed, University of Sadat City, Egypt, maafayed@gmail.com

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Neue Arzneimittel der Nachkriegszeit (IV)

Kunz¹

1952

Archiv der Pharmazie

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Synergistic Effect of a Third Active Glycoside of Senna

Cited by 6 publications

References 1 publication

Potentiating Effect of Sennoside C on Purgative Activity of Sennoside A in Mice

Potentiating Effect of Sennoside C on Purgative Activity of Sennoside A in Mice

Evaluation of the Slimming Effects of Diet Tea in Biochemical and Molecular Meaning

Neue Arzneimittel der Nachkriegszeit (IV)

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