Abstract. Based on the finite element analysis software ANSYS Workbench, studied the fluid-solid coupling numerical simulation of the pipeline centrifugal compressor impeller with the unstructured grid finite volume method and finite element method. The equivalent stress distribution of the impeller, which caused by the centrifugal load, the coupling effect of centrifugal load and aerodynamic load, is analyzed. Based on the fluid components transport theory, the distribution of H 2 S in the flow field inside the impeller is analyzed, and discussed the influence law of pitting corrosion pits on the stress distribution and the H 2 S concentration of the centrifugal compressor impeller blade.