Synoviale Tumoren und tumorähnliche Erkrankungen

Abstract

Synovial tumors comprise a variety of lesions, including those with benign and aggressive neoplastic changes as well as inflammatory causes. In this article we focus on neoplastic tumors. Synovial tumors with other etiologies, such as sarcoidosis, granuloma, synovitis, or gouty arthritis, are not dealt with here. Through a precise differentiation between these disease entities can an optimization of treatment be achieved.

Synovial Tissue Biopsy Collection by Rheumatologists: Ready for Clinical Implementation?

“…Rare systemic proliferative non-infectious conditions and neoplastic conditions such as histiocytositic conditions, sarcoidosis, melanoma, leukemia/lymphoma, and metastasis often can be diagnosed based on pathological changes in other tissues or organs, but these sometimes lack and typical synovial tissue pathological changes may yield a diagnosis (76–78). Histiocytic conditions, such as multicentric reticulohistiocytosis, Langerhans cell histiocytosis, and Erdheim–Chester disease, typically involve tissue infiltration of bones, the reticuloendothelial system and various organs (79–83).…”

De Novo Synovial Chondromatosis following Primary Total Knee Arthroplasty: A Case Report

“…Often, these cartilaginous nodules detach and form intra-articular loose bodies, while the synovial fluid nourishes their growth [5]. The formation of multiple chondroid nodules, osteochondral, or osseous loose bodies is the result of the disease process and usually presents as a monoarthropathy [1,6,7]. When it involves the knee joint, SC is usually restricted to the anterior compartment of the knee and includes the anterior fat pad and suprapatellar pouch [8].…”

“…The etiology of the primary SC is not well understood. Secondary SC is thought to occur as a result of mechanical changes in a joint due to an arthropathy such as osteochondrosis dissecans, recurrent trauma, or previous surgical procedures [1,7]. The diagnosis of SC, in either form, is often missed or delayed due to the fact that symptoms are non-specific and insidious in the onset [5].…”