Syntactic language processing: ERP lesion data on the role of the 
basal ganglia

Kotz, Sonja A.; Frisch, Stefan; Cramon, D. Yves von; Friederici, Angela D.

doi:10.1017/s1355617703970093

Cited by 130 publications

(91 citation statements)

References 36 publications

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“…Furthermore, the use of an implicit manipulation task and the absence of both prime order and block order effects as well as the near absence of correlations between executive and rule parameters suggest that the striatum subserves rule application via language-specific operations. Yet, we do not preclude the possibility that the striatum, which is known to encompass functional circuits of executive functioning (e.g., Middleton & Strick, 2000), also controls lexical output at some post-linguistic level as implied by the data of Friederici et al (1999) and and Kotz et al (2003). This view is also coherent with findings showing that lexical operations such as word retrieval depend on controlled research strategies in the mental lexicon involving prefrontal and striatal structures (e.g., Rosen, Ojemann, Ollinger, & Petersen, 2000).…”

Section: Discussionsupporting

confidence: 75%

“…Similar sentence materials were also used with striatal damaged patients during ERP recollection (PD, vascular disorders). Several authors showed that the P600 component, which was hypothesised to index late stages of grammatical integration, is either absent (Friederici, Kotz, Werheid, Hein, & von Cramon, 2003;Kotz, Frisch, von Cramon, & Friederici, 2003) or reduced in these patients (Friederici, von Cramon, & Kotz, 1999). Such findings led to the assumption that the striatum subserves controlled post-linguistic processes allowing to verify and to integrate the output of early and automatic stages of syntactic processing .…”

Section: Introductionmentioning

confidence: 99%

“…However, intriguingly, this lexical and post-linguistic view of the striatum seems to be restricted to the processing of grammatical categories. Indeed, the investigation of other domains that heavily depend on lexicalised information, such as semantics, showed that striatal damaged patients display a normal N400 component, a marker of semantic incongruence, when tested with sentences that contained semantic restriction violations (e.g., "the volcano was eaten") (Friederici et al, 1999;Kotz et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

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The role of the striatum in sentence processing: Evidence from a priming study in early stages of Huntington's disease

et al. 2008

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The role of sub-cortical structures such as the striatum in language remains a controversial issue. Based on linguistic claims that language processing implies both recovery of lexical information and application of combinatorial rules it has been shown that striatal damaged patients have difficulties applying conjugation rules while lexical recovery of irregular forms is broadly spared (e.g., Ullman, M. T., Corkin, S., Coppola, M., Hickok, G., Growdon, J. H., Koroshetz, W. J., et al. (1997). A neural dissociation within language: Evidence that the mental dictionary is part of declarative memory, and that grammatical rules are processed by the procedural system. Journal of Cognitive Neuroscience, 9(2), 266-276). Here we bolstered the striatum-rule hypothesis by investigating lexical abilities and rule application at the phrasal level.Both processing aspects were assessed in a model of striatal dysfunction, namely Huntington's disease (HD). Using a semantic priming task we compared idiomatic prime sentences involving lexical access to whole phrases (e.g., "Paul has kicked the bucket") with idiom-derived sentences that contained passivation changes involving syntactic movement rules (e.g., "Paul was kicked by the bucket"), word changes (e.g., "Paul has crushed the bucket") or either. Target words that were either idiom-related (e.g., "death") reflecting lexical access to idiom meanings, word-related (e.g., "bail") reflecting lexical access to single words, or unrelated (e.g., "table").HD patients displayed selective abnormalities with passivated sentences whereas priming was normal with idioms and sentences containing only word changes. We argue that the role of the striatum in sentence processing specifically pertains to the application of syntactic movement rules whereas it is not involved in canonical rules required for active structures or in lexical processing aspects. Our findings support the striatum-rule hypothesis but suggest that it should be refined by tracking the particular kind of language rules depending on striatal computations.

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Section: Discussionsupporting

confidence: 75%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The role of the striatum in sentence processing: Evidence from a priming study in early stages of Huntington's disease

et al. 2008

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“…This result is consistent with findings of delayed lexical-semantic activation during semantic priming in some patients with PD (Angwin et al, 2005;Arnott et al, 2001;Grossman et al, 2002). Also worthy of note, Kotz, Frisch, Von Cramon, and Friederici (2003) found that patients with a basal ganglia lesion demonstrated an Table 5. Mean amplitude of the N400 and P600 across electrode clusters for the first and second (repeat) presentation of stimuli Fig.…”

supporting

confidence: 89%

A Neurophysiological Study of Semantic Processing in Parkinson’s Disease

Angwin

Dissanayaka

Moorcroft

et al. 2016

J Int Neuropsychol Soc

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Objectives: Cognitive-linguistic impairments in Parkinson's disease (PD) have been well documented; however, few studies have explored the neurophysiological underpinnings of semantic deficits in PD. This study investigated semantic function in PD using event-related potentials. Methods: Eighteen people with PD and 18 healthy controls performed a semantic judgement task on written word pairs that were either congruent or incongruent. Results: The mean amplitude of the N400 for new incongruent word pairs was similar for both groups, however the onset latency was delayed in the PD group. Further analysis of the data revealed that both groups demonstrated attenuation of the N400 for repeated incongruent trials, as well as attenuation of the P600 component for repeated congruent trials. Conclusions: The presence of N400 congruity and N400 repetition effects in the PD group suggests that semantic processing is generally intact, but with a slower time course as evidenced by the delayed N400. Additional research will be required to determine whether N400 and P600 repetition effects are sensitive to further cognitive decline in PD. (JINS, 2017, 23, 78-89)

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“…Studying language processing in PD allows researchers to analyze the effects of poorly functioning, yet still engaged corticostriato-cortical circuitry during language performance. Some of the studies reviewed in this chapter aimed at examining language processing in PD, to ultimately define the role of the basal ganglia in language processing (e.g., Ullman et al, 1997;Friederici et al, 2003;Grossman et al, 2003;Kotz et al, 2003). In the final section of this chapter, advice for communication guidelines that would guarantee a better quality of life for patients suffering from PD is given.…”

mentioning

confidence: 99%