SyntEyes KTC: higher order statistical eye model for developing keratoconus

Abstract

The synthetic data provided by the proposed keratoconus model closely resembles actual clinical data and may be used for a range of research applications when (sufficient) real data is not available.

Analysing the ocular biometry of new‐born infants

“…CCT, ACD , T , L , r ca , and P L ), from which the synthetic data may be randomly generated. More details on this type of models may be found in our previous works …”

“…Meanwhile the non‐parametric Levene test (or Brown‐Forsythe test) was used to assess the equality of group variances. For more information on the use of these tests we refer to a previous paper on the subject …”

“…More details on this type of models may be found in our previous works. 36,37 Literature model There have been quite a few papers in the literature reporting on the biometry of very young infants, almost all of which provide only mean and standard deviation values or histograms. Meanwhile, raw data is almost never available.…”

Visual and Physiological Optics: where will the journey lead us in 10 years?

“…The same authors established a set of relationships between the cardinal and anti‐cardinal points of a Gaussian system, and illustrated these with extended Pascal's ring diagrams. The last paper presents a stochastic of eye model for keratoconus in various stages of the disease. It describes the generation of an unlimited amount of synthetic biometry sets that may be used for developing and testing new optical correction methods.…”

Personalized Optical Designs and Manipulating Optics: Applications on the Anterior Segment of the Eye

“…Given the large numbers of potential patients for optical correction of presbyopia and cataract, managing keratoconus, or slowing down the progression of myopia, the potential impact of new solutions based on personalized optical designs is undoubtedly tremendous and will offer both remarkable opportunities and challenges in a wide range of anterior segment applications. Combining the technological advances in aberrometry and three-dimensional anterior segment imaging techniques with dedicated ray-tracing and processing tools will allow building patient-specific eye models for the selection of the contact and/or intraocular lens design that provides the best optical quality [1][2][3].…”