Synthese und Hydrolyse von 3,6-Dialkyl-4,5-bis[dialkylamino]-1,2-benzochinonen

Reconciling Icetexane Biosynthetic Connections with Their Chemical Synthesis: Total Synthesis of (±)-5,6-Dihydro-6α-hydroxysalviasperanol, (±)-Brussonol, and (±)-Abrotanone

“…Perusal of the literature revealed only a handful of examples of such a transformation. Of these, we were drawn to a report by Löwer and co-workers that suggested this process could be mediated by Cu 2+ . In the event, treatment of 3 with Cu(NO 3 ) 2 ·3H 2 O and morpholine in MeOH led to formation of hemiaminal 20 (Scheme ).…”