Syntheses and metal complexes of a quadridentate NNSS ligand derived from S-benzyl dithiocarbazate (H2L) and crystal structure of the complex CuL

Synthesis and characterization of bis(2-aminophenyl)disulphide diimine derivatives and their ruthenium complexes

“…The ortho-substituted benzaldehydes, such as the 2-chloro and 2-hydroxy, reacted spontaneously with the diamines at room temperature to give the corresponding diimines (5) and (9) in quantitative yield. In all the other cases, the diamines were boiled under reflux with the benzaldehydes for 3-4 h. 3-Hydroxy-or 3-methoxy-benzaldehyde did not react with the dithiophenyldiamine even after refluxing in EtOH for 2 days.…”

“…Ruthenium(II) complexes of (3), (5), (8), (9) To a stirred solution of diimine (1 mmol) in EtOH (20 cm 3 ), RuCl 3 AE 3H 2 O (2 mmol) and L (2 mmol) (L ¼ 2,2 0 -bipyridine or 1,10-phenanthroline or 3,4-diaminotoluene or pyridine or PPh 3 ) were added. The resulting solution was refluxed for 3 h, filtered and concentrated to 1/10th of its original vol.…”

“…spectra of the diimine ligands (1)(2)(3)(4)(5)(6)(7)(8)(9) showed strong bands at 1600-1650 cm )1 that were assigned to the C@N stretching frequency. The m C@N peak in the metal complexes showed red shifts of ca.…”

“…There has been considerable interest in the chemistry of metal complexes of ligands containing O,N; O,S; N,N; N,S and S,S donor atoms, owing to the industrial, carcinostatic, antitumour, antiviral and antimalarial activity of the complexes derived from them [4][5][6][7][8][9]. The disulfide group is well recognized as a potential binding site for metal ions in biological systems.…”

Transition Metal Bis(2-Bromophenyl)disulfide Complexes

“…Binuclear species with bridging sulphur atoms play an important role in active sites of metalloenzymes such as nitrogenase, hydrogenase or CO-dehydrogenase. 5,6 Furthermore, conversion of thiols to disulfides is important from both biological and synthetic point of view. 7,8 Dehydroascorbic acid, flavins, cytochromes oxidizes thiols to control the cellular redox potential and prevent oxidative damage in biological systems.…”