Synthesis and Antibacterial Activities of 4‐Pyrrolidinylthio Carbapenems: Containing Heteroaromatics as a Side Chain.

Abstract

Synthesis and Antibacterial Activities of 4-Pyrrolidinylthio Carbapenems: Containing Heteroaromatics as a Side Chain. -A variety of the new carbapenem derivatives (XI) (10 examples) are synthesized and evaluated for their in vitro antibacterial activities. Compounds (XIa) and (XIb) show the most potent activity. -(CHO, H.-W.; OH, C.-H.; LEE, J.-S.; LEE, S.-C.; CHOI, J.-H.; CHO*, J.-H.; Arch.