Synthesis and antibacterial activity of iron-hexacyanocobaltate nanoparticles

Abstract

This paper deals with the synthesis and characterization of iron-hexacyanocobaltate (FeHCC) and its antibacterial properties. The nanoparticles were prepared by a facile co-precipitation technique. Crystal structure, particle morphology, and elemental composition were determined using X-ray Powder Diffraction, X-ray fluorescence spectroscopy, Transmission Electron Microscopy (TEM), and Infrared Spectroscopy (IR). The antibacterial activity of the FeHCC nanoparticles was tested against Escherichia coli and Staphylococcus aureus as models for Gram-negative and Gram-positive bacteria, respectively, by bacterial counting method and microscopic visualization (TEM, FEG-SEM, and fluorescence microscopy). The results showed that the FeHCC nanoparticles bind to the bacterial cells, inhibit bacterial growth in a dose- and time-dependent manner, inducing a loss of the membrane potential, the production of reactive oxygen species and the release of macromolecules (nucleic acids and proteins) in the extracellular environment. To the best of our knowledge, this is the first study reporting the antimicrobial effects of metal-hexacyanometallates suggesting practical uses of these materials in different areas, such as self-cleaning surfaces or food packaging.

Loading and release of the complex [Pt(DTBTA)(DMSO)Cl]Cl·CHCl3 with the 2,2′-dithiobis(benzothiazole) ligand into mesoporous silica and studies of antiproliferative activity on MCF-7 cells

“…According to IUPAC [25] the characteristic type IV-isotherms and type I-isotherms were obtained for the MCM41 and MCM41-NH 2 loaded samples and were similar to the ones of the unloaded supports. Similar results have been obtained for other drug loaded on the same supports [17,21,22]. S BET and V t were reported in Table 1.…”

“…Drug delivery systems are able to improve the permeability retention effect, safety, pharmacokinetics properties and bioavailability of the therapeutic substances in treatment of tumour [15]. MCM41 mesoporous silica was first proposed as drug delivery device in 2000 [16,17]. This mesoporous has a high surface area and pore volume that allows it to host a large amount of a determined biologically active molecule, while its ordered pore network allows fine control of the molecule load and release kinetics [18,19].…”

Graphene Oxide Carboxymethylcellulose Nanocomposite for Dressing Materials

“…P. aeruginosa and S. aureus cells were grown for 24 h in the presence of CMC, CMC6/Exf -GO and Exf -GO, prior to their imaging by means of a fluorescence microscope (Carl Zeiss, Oberkochen, Germany), as described by [38]. Briefly, bacterial cells were diluted 10 times in phosphate buffer saline (PBS) and stained with a 1:1 (v/v) mixture of acridine orange (100 µg/mL) and ethidium bromide (100 µg/mL), and were then immediately imaged at 1000× magnification by using excitation and emission wavelength of 488 nm and 550 nm, respectively.…”

Effect of Water and Alkali‐Ion Content on the Structure of Manganese(II) Hexacyanoferrate(II) by a Joint Operando X‐ray Absorption Spectroscopy and Chemometric Approach

“…The cyanides within the structure bridge Fe and M ions, which in turn constitute the electroactive centers of the framework. PBAs have found employment in several applications because of their structure/activity properties . Among PBAs, manganese hexacyanoferrate is constituted only by earth‐abundant elements and displays high operational voltages and relatively high specific capacities in aprotic electrolytes .…”