Synthesis and Anticancer Activity of Bagasse Xylan/Resveratrol Graft-Esterified Composite Nanoderivative

Zhao, Bin; Li, Heping; Su, Yue; Tian, Kexin; Zou, Zhiming; Wang, Wenli

doi:10.3390/ma15155166

Cited by 3 publications

(1 citation statement)

References 38 publications

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“…Both types of xylan–curcumin nanoparticles offer promise as polyphenol encapsulates, effectively delivering curcumin to CRC cells. In addition, resveratrol encapsulated in bagasse xylan/resveratrol graft-esterified nanoparticles demonstrated anti-cancer potential that could be used in CRC [ 164 ].…”

Section: Carriers and Encapsulates Based On Hemicellulosesmentioning

confidence: 99%

Encapsulation of Polyphenolic Compounds Based on Hemicelluloses to Enhance Treatment of Inflammatory Bowel Diseases and Colorectal Cancer

Caban

Lewandowska

2023

Molecules

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Inflammatory bowel diseases (IBD) and colorectal cancer (CRC) are difficult to cure, and available treatment is associated with troubling side effects. In addition, current therapies have limited efficacy and are characterized by high costs, and a large segment of the IBD and CRC patients are refractive to the treatment. Moreover, presently used anti-IBD therapies in the clinics are primarily aimed on the symptomatic control. That is why new agents with therapeutic potential against IBD and CRC are required. Currently, polyphenols have received great attention in the pharmaceutical industry and in medicine due to their health-promoting properties. They may exert anti-inflammatory, anti-oxidative, and anti-cancer activity, via inhibiting production of pro-inflammatory cytokines and enzymes or factors associated with carcinogenesis (e.g., matrix metalloproteinases, vascular endothelial growth factor), suggesting they may have therapeutic potential against IBD and CRC. However, their use is limited under both processing conditions or gastrointestinal interactions, reducing their stability and hence their bioaccessibility and bioavailability. Therefore, there is a need for more effective carriers that could be used for encapsulation of polyphenolic compounds. In recent years, natural polysaccharides have been proposed for creating carriers used in the synthesis of polyphenol encapsulates. Among these, hemicelluloses are particularly noteworthy, being characterized by good biocompatibility, biodegradation, low immunogenicity, and pro-health activity. They may also demonstrate synergy with the polyphenol payload. This review discusses the utility and potential of hemicellulose-based encapsulations of polyphenols as support for treatment of IBD and CRC.

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Section: Carriers and Encapsulates Based On Hemicellulosesmentioning

confidence: 99%

Encapsulation of Polyphenolic Compounds Based on Hemicelluloses to Enhance Treatment of Inflammatory Bowel Diseases and Colorectal Cancer

Caban

Lewandowska

2023

Molecules

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A fast, reliable, low‐cost, and efficient xylan extraction for xylooligosaccharides production

Kumari,

Nagar,

Goyal

et al. 2024

Biofuels Bioprod Bioref

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A fast, reliable, low‐cost, and efficient method for the recovery of xylan from agro‐residue materials is needed to improve the use of xylan in industrial processes. Xylan was extracted from two agrowastes (corncobs and wheat bran) using a cost‐effective alkali extraction method. The characteristic band patterns and bending vibrations associated with hemicellulose and beta glycoside linkage could be seen in the corncob‐extracted xylan (CCEx) and wheatbran‐extracted xylan (WBEx). Scanning electron microscopy (SEM) analysis showed that the extracted xylans consisted of aggregated and nonaggregated particles with irregular morphology and rough surfaces. Particle‐size analysis displayed average sizes of 205.6, 210.8, and 794.2 nm for commercial beechwood xylan (Bx), CCEx, and WBEx, respectively. Alkali extraction was performed with different concentrations of NaOH, from 5% to 20%, with a solid–liquid ratio of 1:20. It was found that 82.90 and 76.77% of xylan were extracted from corncob and wheat bran, respectively, which represents a higher yield obtained in a shorter duration in comparison with studies in the literature. The enzymatic hydrolysis of wheat bran and corncob that used 250 IU/mL of Enterobacter hormaechie KS1 xylanase yielded 334.38 and 162.35 mg/g of xylooligosaccharides. Their properties were studied and were found to be very similar to those of commercial xylan. They could reduce costs if applied in industry.

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Ultra-sensitive turn-on fluorescent sensor based on β-cyclodextrin-stabilized melamine-derived carbon dots for the highly selective dual-detection of dopamine

Sangubotla

Kim

2023

Ceramics International

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Synthesis and Anticancer Activity of Bagasse Xylan/Resveratrol Graft-Esterified Composite Nanoderivative

Cited by 3 publications

References 38 publications

Encapsulation of Polyphenolic Compounds Based on Hemicelluloses to Enhance Treatment of Inflammatory Bowel Diseases and Colorectal Cancer

Encapsulation of Polyphenolic Compounds Based on Hemicelluloses to Enhance Treatment of Inflammatory Bowel Diseases and Colorectal Cancer

A fast, reliable, low‐cost, and efficient xylan extraction for xylooligosaccharides production

Ultra-sensitive turn-on fluorescent sensor based on β-cyclodextrin-stabilized melamine-derived carbon dots for the highly selective dual-detection of dopamine

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