Synthesis and antimicrobial activities of some novel bis-pyrazole derivatives containing a hydrophosphoryl unit

Crystal structure of ethyl 5-amino-3-(methylthio)-1-(1-phenyl-5-(thiophen-2-yl)-1H-pyrazole-3-carbonyl)-1H-pyrazole-4-carboxylate, C21H19N5O3S2

“…Bis-pyrazoles have received great attention since they show various interesting applications [1][2][3]. Cell re nement and data reduction were carried out by Bruker SAINT [5].…”

Synthesis of Some Novel Thiadiazaphosphole, Oxazaphospholothiadiazaphosphole, Thiadiazaphosphinine, and Phosphonates Containing a 1,2,4‐Triazine Moiety

“…They were demonstrated to be pesticides , herbicides , antifungal , anti‐inflammatory , anti‐HIV , anticancer , and good cytotoxic on K562 and colo205 cancerous cells . These aforementioned reasons with our interest in organophosphorus chemistry encouraged us to synthesize new organophosphorus compounds incorporating 1,2,4‐triazinone moiety through reaction of 4‐amino‐6‐methyl‐3‐sulfanyl‐1,2,4‐triazin‐5(4 H )‐one ( 1 ) with different phosphorus reagents.…”

One‐Pot Synthesis of Some Dynamic 2‐Substituted Benzoxazinones and Their Corresponding Qinazolinones of Anticipated Biological Activity

“…Reacting with different nitrogen nucleophiles, benzoxazinones are considered scaffold for the synthesis of the corresponding quinazolinones which are potent inhibitors of the epidermal growth factor (EGFR) [20][21][22][23][24][25][26][27][28]. The EGFR is cellular trans-membrane tyrosine kinases that are overexpressed in a significant number of human tumors, e.g.…”