Synthesis and Antimicrobial Activity of Novel Phosphorus Heterocycles with Exocyclic P-C Link

Synthesis, spectral characterization and bioassay of 3,3′-(1,4-phenylene)-bis[2-alkoxycarbonyl-alkyl)-2-thio-benzoxa-phosphinines]

“…The chemical shift of the a carbon atom to the amino acid ester group appeared at 49.5-52.0 ppm. The remaining carbon signals were observed in their expected regions [10]. Compounds 3a-j showed a phosphorus-31 resonance signals in the range of 58.95-62.14 ppm [10,11].…”

“…The remaining carbon signals were observed in their expected regions [10]. Compounds 3a-j showed a phosphorus-31 resonance signals in the range of 58.95-62.14 ppm [10,11]. LCMS of 3a, 3e, 3i and 3j gave molecular ions and diagnostic daughter ions at their expected m/z values.…”

Synthesis, characterization and antimicrobial activity of (5- bromo-5-nitro-2-oxido-1,3,2-dioxaphosphinan-2-yl)amino acid esters

“…Characteristic absorption bands in IR spectra for the title compounds were observed in the regions 3418--3441, 1739-1748, 1554-1564, 1249-1258 and 552-563 cm -1 for N-H, C=O, NO 2 , P=O and C-Br, respectively. 9 In the 1 H-NMR spectra, 10 showed carbon chemical shifts in the expected region. 10 The 31 P chemical shifts 11 were observed at δ 7.24-13.2 ppm for 3a-l as a singlet.…”

Synthesis and Bioactivity of Some New 2‐(Alkoxy carbonyl alkyl)‐6‐bromo‐3,4‐dihydro‐3‐(α‐methyl benzyl)‐2‐oxo‐benzo[e] [2H‐1,3,2‐oxazaphosphinine] Derivatives

“…8 The remaining carbon signals were observed in the expected regions. 5,6 The 31 P NMR spectra of 4a-4j showed phosphorus resonance signals 5,9 in the region δ 8.04 to 2.19. The mass spectral data of the representative compound 4g…”

“…5,6 The aromatic protons of 4a-4j resonated as multiplets in the region δ 7.85-6.54. The proton attached to the exocyclic chiral methine carbon exhibited a multiplet in δ 5.31-5.00 due to its interaction with the methyl group attached to the same carbon.…”