Synthesis and antimicrobial activity of some new indole containing isoxazolines and phthalimidoxy derivatives of thiazolidinone and thiohydantoin

Synthesis and Antibacterial Activity of New Spiro[thiadiazoline-(pyrazolo[3,4-d]pyrimidine)] Derivatives

“…Among the many heterocyclic compounds containing nitrogen, the pyrazolopyrimidine ring is very interesting and versatile scaffold for the synthesis of potential drugs or molecular tools (Figure 1). Among their many applications, pyrazolo [3,4-d]pyrimidines (Figure 2) were used as inhibitor kinases [1,2] antiviral agents [3,4], adenosine antagonists [5][6][7], glutamate modulators [8], antituberculosis agents [3], and as antibiotics inhibit bacterial growth [9,10].…”

Polyethylene Glycol Mediated, One‐Pot, Three‐Component Synthetic Protocol for Novel 3‐[3‐Substituted‐5‐mercapto‐1,2,4‐triazol‐4‐yl]‐spiro‐(indan‐1′,2‐thiazolidin)‐4‐ones as New Class of Potential Antimicrobial and Antitubercular Agents

“…Thiazolidinone, an important class of sulfur‐containing and nitrogen‐containing heterocycles, has received extensive interest in the recent past owing to their clinical use and wide application as toxic agents in cells of pathogenic organism . Among them, several thiazolidinone derivatives were designed and synthesized as antibacterial , antifungal , anticonvulsant , anti‐HIV , and antitubercular agents. Similarly, the importance of 1,2,4‐triazoles as versatile pharmacodynamic moiety has been well documented in many of its derivatives, which exhibited anti‐inflammatory , antiviral , antimycotic , and antimicrobial activities .…”

Synthesis and Biological Evaluation of Pyrazoline Derivatives Bearing an Indole Moiety as New Antimicrobial Agents

“…Indolmycin is an example of antibacterial agents bearing an indole ring with anti‐staphylococcal activity 25, 26. Furthermore, some researchers synthesized indole derivatives and evaluated their antimicrobial activity against bacterial and fungal strains 27–30.…”