No abstract

3-Methylpyrazol-5-one 3 reacts with substituted benzaldehydes 4a-d in the presence of anhydrous sodium acetate to produce the corresponding 4-arylidene-5-methyl-2,4-dihydro-pyrazol-3-ones 5a-d and the condensation of 5a-d with 2-bromoalkoxy-1H-isoindole-1, 3-(2H)-diones 2a-c furnished corresponding 2-[2-(4-arylidene-3-methyl-5-oxo-4,5-dihydro-pyrazol-1-yl)alkoxy]-isoindole-1,3-diones 6a-l, which on cyclisation with o-phenylendiamine give titled compounds 7a-l. All the synthesized compounds have been characterized by elemental analysis and spectral data and screened for their antibacterial properties against various bacterial strains in order to obtain chemotherapeutic properties.

Thiazole derivatives R 0260Synthesis and Pharmacological Studies of Some Phthalimidoxy Substituted Spiro-thiazolidinone Derivatives of Isatin. -A variety of title compounds (IX) is synthesized starting from chalcone (I) and evaluated for in vitro antifungal and antibacterial effects. Derivative (IXc) is found to be the most active product. -(BHAMBI, D.; SHARMA, C.; SHARMA, S.; SALVI, V. K.; TALESARA*, G. L.; Indian J.

Fused pyridine derivatives R 0450 Synthesis and Antimicrobial Evaluation of Some Alkoxyphthalimide Derivatives of Naphthyridine. -The majority of the synthesized title compounds (IX) and (XI) show moderate to strong antimicrobial activity. -(BHAMBI, D.; SALVI, V. K.; BAPNA, A.; PEMAWAT, G.; TALESARA*, G. L.; Indian J. Chem., Sect. B: Org.

In this study, a series of 2-[(4-substituted phthalazine-1-yl