Synthesis and antimicrobial activity of 6-aryl-3,4-dimethyl-N-phenyl-2-oxo-1,2,3,6-tetrahydropyrimidine-5-carboxamides

Crystal structure of 1,2-bis(4-methoxyphenyl)-2-((3-(trifluoromethyl)phenyl)amino)ethan-1-one, C23H20F3NO3

“…For some substituted carboxamides their lipid-lowering e ects were studied in hyperlipidemic rats [3]. Also, several carboxamide derivatives are known to show antimicrobial, antiviral and antitumor activity [4][5][6][7][8]. On the other hand, some of heterocyclic derivatives containing a carboxamide moiety possess wide-spread use because of their anti-microbial [9], anti-arrhythmic, serotonin antagonist and anti-anxiety activities [10] and monoamino oxidase inhibitors activities [11] and are also well known as expected potential pharmaceutical carriers for catatonic agents [12].…”