Synthesis and antimicrobial activity of styryl/pyrrolyl/pyrazolyl sulfonylmethyl-1,3,4-oxadiazolyl amines and styryl/pyrrolyl/pyrazolyl sulfonylmethyl-1,3,4-thiadiazolyl amines

Green Approach for the Synthesis of a New Class of Diamidomethane‐linked Benzazolyl Pyrazoles and Evaluation as Antifungals

“…There are various methods for the oxidation of pyrazolines to pyrazoles . However, we have reported the oxidation of differently substituted pyrazolines adopting chloranil in xylene and MnO 2 in benzene . However, we focused our interest towards the synthesis of pyrazoles using green methodology.…”

Recent Advances for the Synthesis of N‐Unsubstituted Pyrroles

“…The classical protocol based on the reaction between alkenes 286, 287 and TosMIC 263 a under basic conditions for the synthesis of pyrrolyl sulfonylmethyl-1,3,4-oxadiazolyl/thiadiazolyl amines 288, 289 was used group of G. Sravya et al (Scheme 96). [94] A new class of pyridinylcarbamoylmethyl pyrrolylcarboxamides 292 was prepared [95] from the synthetic intermediate pyridinylcarbamoylmethyl cinnamamide 291 adopting simple and versatile synthetic methodologies. All the synthesized compounds were evaluated for antioxidant activity (Scheme 97).…”

The crystal structure of 2-(3-(4-bromophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)-8H-indeno[1,2-d]thiazole, C25H17BrFN3S

“…Indeno [1,2-d]thiazoles act as A1 adenosine receptor agonist allosteric enhancers [5] and anorectic agents [6]. Heterocycles containing pyrazole and thiazole moieties are biologically active and show some medicinal activities [7][8][9]. The most common synthetic methods for pyrazoles involve a treatment of 1,3-difunctional compounds with hydrazines [10], whereas thiazoles are commonly synthesized through Hantzsch, Gabriel, and Cook-Heilborn's syntheses [11].…”