Synthesis and antioxidant activity of novel 15‐alkyl/aryl‐13, 17‐dihydro‐15λ<sup>5</sup>‐dibenzo [e, k] [1, 3, 7, 10, 2] dioxadiazaphosphacyclotridecin‐15‐selones/thiones/ones

Naidu, K. Reddi Mohan; Kumar, Manjeet; Dadapeer, E.; Babu, K. Ramesh; Raju, C. Naga; Ghosh, Sunil K.

doi:10.1002/jhet.556

Cited by 10 publications

(1 citation statement)

References 19 publications

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“…The substituted 1,3,7,10‐dioxadiazaphosphacyclotridecinones ( I ) and 1,3,2‐diazaphosphole‐1‐oxides ( II ) are structurally important macrophosphorus heterocyclic molecules, which are active antioxidants shown in Figure .…”

Section: Antioxidant Activitymentioning

confidence: 99%

Synthesis and Antioxidant Properties of New Substituted 8‐Methyl‐6‐phenyl‐5,6‐dihydro‐4H‐1,3,2‐benzodioxaphosphocine‐2‐oxide Derivatives

Prasad

Krishna

Sudha

et al. 2016

Journal of Heterocyclic Chem

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A new route for the synthesis of substituted 8‐methyl‐6‐phenyl‐5,6‐dihydro‐4H‐1,3,2‐benzodioxaphosphocine‐2‐oxide derivatives has been developed by using cinnamic acid and p‐cresol via condensation, reduction, and followed by phosphorylation steps. The title compounds were characterized by IR, 1H, 13C, 31P, and mass spectral studies and elemental analysis. The title compounds have been investigated for their antioxidant activity with respect to their IC50 values using 2,2‐diphenyl‐1‐picrylhydrazyl, NO radical scavenging activities, and reducing power assay. The results obtained from the aforementioned methods revealed that 2‐phenylamino derivatives have shown greater free radical scavenging activity when compared with those of the phenoxy derivatives and is attributed to the presence of secondary amino group, which is able to produce free radicals easily.

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Section: Antioxidant Activitymentioning

confidence: 99%

Synthesis and Antioxidant Properties of New Substituted 8‐Methyl‐6‐phenyl‐5,6‐dihydro‐4H‐1,3,2‐benzodioxaphosphocine‐2‐oxide Derivatives

Prasad

Krishna

Sudha

et al. 2016

Journal of Heterocyclic Chem

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Organic Compounds Containing Bonds between Se or Te with P, As, Sb and Bi

Murai

2014

Patai's Chemistry of Functional Groups

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This chapter describes syntheses, structures, and reactions of the compounds with phosphorus‐selenium double bonds and with at least one carbon‐phosphorus single bond and of their heavier congeners. Among them, phosphane selenides have been the most deeply studied and used as Lewis base catalysts, metal ligands, molecular sensors, and stating materials leading to selenium‐containing nanoparticles. The coupling constants between the phosphorus and selenium atoms are informative on the basicity of the phosphanes. Phosphinoselenoic acid chlorides and secondary phosphanes are frequently used precursors to give a range of phosphinoselenoic acid derivatives, whereas selenation of dichlorophosphanes leads to phosphonoselenoic acid dichlorides, which are converted to a variety of acid derivatives. The selenation of phosphinites also gives phosphinoselenoic acid O ‐esters. Stereochemical course of the substitution reaction at P ‐chiral phosphorus center in the substitution reaction has been elucidated. Some reactions of dimers of diselenoxophosphanes such as Woollin's reagent are also shown. The chapter finally describes examples of phosphane tellurides, arsenic, antimony, and bismuth isologues of phosphane selenides, although these are fewer.

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Synthesis and Anti‐Oxidant Activity of (5E,9E)‐16‐(Substituted)‐7,8‐dihydro‐16λ⁵‐dibenzo[d,l][1,3,7,10,2]dioxadiazaphosphacyclotridecine‐16‐ones

Reddy

Chinthaparthi

Sekhar

et al. 2012

Archiv der Pharmazie

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A new class of biologically active 13-membered phosphorus-macroheterocycles (6a-l) were conveniently synthesized from 1,2-bis(salicylidene amino)-phenylene (1), by treating with phosporusoxychloride (3) and followed by reacting with various aromatic thiols and amines (5f-l) in one path, and in another path 1 was directly treated with various phosphorodichloridates (2a-e) in the presence of triethylamine at 0-10°C under N(2) atmosphere in THF. All the title compounds were confirmed by analytical and spectral data (IR, (1) H-, (13) C-, (31) P-NMR, and mass spectra) and screened for anti-oxidant activity. Among these compounds, 6k, 6e, and 6l containing nitro, fluoro, and chloro groups as substituents on the phenyl ring exhibited high anti-oxidant activity with effective inhibitory concentration (IC(50) ) values.

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Synthesis and antioxidant activity of novel 15‐alkyl/aryl‐13, 17‐dihydro‐15λ⁵‐dibenzo [e, k] [1, 3, 7, 10, 2] dioxadiazaphosphacyclotridecin‐15‐selones/thiones/ones

Cited by 10 publications

References 19 publications

Synthesis and Antioxidant Properties of New Substituted 8‐Methyl‐6‐phenyl‐5,6‐dihydro‐4H‐1,3,2‐benzodioxaphosphocine‐2‐oxide Derivatives

Synthesis and Antioxidant Properties of New Substituted 8‐Methyl‐6‐phenyl‐5,6‐dihydro‐4H‐1,3,2‐benzodioxaphosphocine‐2‐oxide Derivatives

Organic Compounds Containing Bonds between Se or Te with P, As, Sb and Bi

Synthesis and Anti‐Oxidant Activity of (5E,9E)‐16‐(Substituted)‐7,8‐dihydro‐16λ⁵‐dibenzo[d,l][1,3,7,10,2]dioxadiazaphosphacyclotridecine‐16‐ones

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Synthesis and antioxidant activity of novel 15‐alkyl/aryl‐13, 17‐dihydro‐15λ5‐dibenzo [e, k] [1, 3, 7, 10, 2] dioxadiazaphosphacyclotridecin‐15‐selones/thiones/ones

Cited by 10 publications

References 19 publications

Synthesis and Antioxidant Properties of New Substituted 8‐Methyl‐6‐phenyl‐5,6‐dihydro‐4H‐1,3,2‐benzodioxaphosphocine‐2‐oxide Derivatives

Synthesis and Antioxidant Properties of New Substituted 8‐Methyl‐6‐phenyl‐5,6‐dihydro‐4H‐1,3,2‐benzodioxaphosphocine‐2‐oxide Derivatives

Organic Compounds Containing Bonds between Se or Te with P, As, Sb and Bi

Synthesis and Anti‐Oxidant Activity of (5E,9E)‐16‐(Substituted)‐7,8‐dihydro‐16λ5‐dibenzo[d,l][1,3,7,10,2]dioxadiazaphosphacyclotridecine‐16‐ones

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Synthesis and antioxidant activity of novel 15‐alkyl/aryl‐13, 17‐dihydro‐15λ⁵‐dibenzo [e, k] [1, 3, 7, 10, 2] dioxadiazaphosphacyclotridecin‐15‐selones/thiones/ones

Synthesis and Anti‐Oxidant Activity of (5E,9E)‐16‐(Substituted)‐7,8‐dihydro‐16λ⁵‐dibenzo[d,l][1,3,7,10,2]dioxadiazaphosphacyclotridecine‐16‐ones