Synthesis and antitumor studies on novel Co(II), Ni(II) and Cu(II) metal complexes of bis(3-acetylcoumarin)thiocarbohydrazone

Copper(II) complexes of coumarin-derived Schiff bases and their anti-Candida activity

“…In more recent years there have been numerous reports highlighting the significant biological activity of Cu(II) Schiff base complexes [40][41][42][43][44][45][46]. Patil et al detailed the preparation of Co(II), Ni(II) and Cu(II) complexes with 1,2,4-triazole-derived coumarin Schiff bases and assessed their biological activity [47].…”

Synthesis, Crystal Structure and Theoretical Calculation of a Novel Nickel(II) Complex with Dibromotyrosine and 1,10-Phenanthroline

“…13 Recently, a series of crystal structures of nickel complexes have been reported, which have demonstrated promising cytotoxic activity and a good activity in the inhibition of tumor cell proliferation. [14][15][16] In this paper, we describe the preparation, characterization and crystal structure of a novel nickel complex, [Ni(phen)(C 9 H 8 Br 2 NO 3 ) 2 ·2CH 3 OH·2H 2 O], which was derived from 3,5-dibromo-L-tyrosine, 1,10-Phenanthroline and Ni(II). Additionally, based on crystal data, density functional theory (DFT) studies of the title complex were performed using the Gaussian 03 program suite.…”

Some Novel Schiff Bases from Pyruvic Acid with Amines Containing N & S Donor Atoms: Synthesis, Spectral Studies and X-Ray Crystal Structures

“…In recent decades, much attention has been focused on Schiff bases derived from thyldithiocarbazate and S-n-octyldithiocarbazate [1] [2] [3] [4] as well as thiocarbohydrazide [5] [6] [7] and substituted thiosemicarbazide [8]. These dithiocarbazates were condensed with carbonyl compounds such as pyruvic acid to synthesize several novel Schiff bases which could lead to many potential applications.…”

“…This is because they contain mixed hard and soft donor atoms nitrogen, oxygen and sulfur which are ideal as chelating agents for metal ions. Most of the organic chelators are capable of exhibiting a wide range of biological potentials such as anticancer [1] [7] [8] [9] [10], antibacterial [5] [7] [11] [12], antifungal [5] [13]. They also have other applications as catalysts in reactions or as photoactive materials [14].…”