Synthesis and Biological Activity of 3-Spiro[adamantane-2,3′-isoquinolines]

Synthesis and Crystal Structures of Two Novel O, N-Containing Spiro Compounds

“…Spiro compounds with special structures and functions have been reported to possess diverse biological and pharmaceutical properties, such as antiplasmodias [1], antibacterial [2,3], antiviral [4], anxiolytic [5], estrogen potentiating [6], anticancer [7,8] antihistamic [9] and antiproliferative [10] agents. Application of spiro compounds in industry [11,12], catalysis [13] and hole-transporting materials [14] has been triggered great interest in recent years.…”

Synthesis and Crystal Structures of Two New Oxaspirocyclic Compounds

“…In recent years, many efforts have been devoted to the preparation and characterization of spiro compounds due to diverse industrial and biomedical applications in medicine [1][2][3], catalysis [4], 18F-radiolabeling [5] and optical material [6][7][8]. The asymmetric characteristic of the molecules, owing to the chiral spiro carbon, is one of the important criteria of the biological activities.…”

Spiro Derivatives in the Discovery of New Pesticides: A Research Review

“…Spiro compounds are widely used in the medical field due to their fungicide, bactericidal, , antidisease, antiviral, , anticancer, , antitumor, and antioxidant properties. Despite their wide application in these areas, between 2010 and 2021 there were fewer than 140 reports of their use in the field of pesticides, although such applications are increasing every year (Figure , left).…”