Synthesis and Biological Activity of Novel Diphenyl <i>N</i>- Substituted Carbamimidoylphosphoramidate Derivatives

Subramanyam, Ch.; Ramana, K. V.; Syed, Rabbani; Adam, S.; Raju, C. Naga

doi:10.1080/10426507.2012.745075

Cited by 11 publications

(5 citation statements)

References 17 publications

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“…The chemical structures of all the title compounds 7a-e and 8a-e were characterized by IR, 1 H, 13 C, 31 P NMR, mass spectral data and elemental analyses and their data were presented in the experimental section. IR absorptions in the regions 3345-3308, 1236-1210 and 1018-1012 cm -1 were assigned to NH, P=O and P-O-C stretching vibrations respectively for the title compounds (Subramanyam et al, 2013). The 1 H NMR spectra gave signals due to Ar-H in the range of δ 8.13-6.82 ppm.…”

Section: Chemistrymentioning

confidence: 96%

Ultrasound-promoted solvent-free synthesis of some new α-aminophosphonates as potential antioxidants

Basha¹,

Subramanyam²,

Rao³

2020

Main Group Metal Chemistry

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Ultrasonic irradiation has been adopted in order to achieve an efficient synthesis of some novel α-aminophosphonates by Pudovik reaction. Major benefits of this method are as follows: eco-friendly, free of catalyst, high yielding, uncomplicated work-up procedure, short reaction time, and solvent free condition. Spectral characterisation and elemental analysis of the synthesized samples was carried out. In vitro antioxidant activity of the title compounds was screened by DPPH˙, O2-˙ and NO˙ scavenging methods. Good activity was shown by most of the compounds as compared with the standards.

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Section: Chemistrymentioning

confidence: 96%

Ultrasound-promoted solvent-free synthesis of some new α-aminophosphonates as potential antioxidants

Basha¹,

Subramanyam²,

Rao³

2020

Main Group Metal Chemistry

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“…G‐Type (German‐agents) CWAs were developed starting from 1930s to 1940s, and include Cyanophosphoramidate, [20] Tabun (GA), [21] Sarin (GB), [22] Soman (GD) [23] and Cyclosarin (GF) [24] …”

Section: Classification Of Op Cwasmentioning

confidence: 99%

“…Today, OP CWAs can be classified into three main groups: G-type, V-type and, the most recent, Atype (also called Novichok) (Figure 1). [17][18][19] G-Type (German-agents) CWAs were developed starting from 1930s to 1940s, and include Cyanophosphoramidate, [20] Tabun (GA), [21] Sarin (GB), [22] Soman (GD) [23] and Cyclosarin (GF). [24] V-Type (venomousagents) CWAs, discovered after World War 2, are methylphosphothioates and collect two compounds: VX [25] and RVX.…”

Section: Classification Of Op Cwasmentioning

confidence: 99%

Supramolecular Sensing of Chemical Warfare Agents

et al. 2021

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Chemical warfare agents are a class of organic molecules used as chemical weapons due to their high toxicity and lethal effects. For this reason, the fast detection of these compounds in the environment is crucial. Traditional detection methods are based on instrumental techniques, such as mass spectrometry or HPLC, however the use of molecular sensors able to change a detectable property (e. g., luminescence, color, electrical resistance) can be cheaper and faster. Today, molecular sensing of chemical warfare agents is mainly based on the “covalent approach”, in which the sensor reacts with the analyte, or on the “supramolecular approach”, which involves the formation of non‐covalent interactions between the sensor and the analyte. This Review is focused on the recent developments of supramolecular sensors of organophosphorus chemical warfare agents (from 2013). In particular, supramolecular sensors are classified by function of the sensing mechanism: i) Lewis Acids, ii) hydrogen bonds, iii) macrocyclic hosts, iv) multi‐topic sensors, v) nanosensors. It is shown how the supramolecular non‐covalent approach leads to a reversible sensing and higher selectivity towards the selected analyte respect to other interfering molecules.

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“…The first generation of NA, also called "G-Type" (German-agents), was discovered in the late 1930s and early 1940s. They include the Cyanophosphoramidate [19], Tabun (GA) [20] and methylfluorophosphonates compounds, such as Sarin (GB) [21], Soman (GD) [22] and Cyclosarin (GF) [23] (Figure 1).…”

Section: Definition Of Nasmentioning

confidence: 99%

Catalytic Degradation of Nerve Agents

et al. 2020

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Nerve agents (NAs) are a group of highly toxic organophosphorus compounds developed before World War II. They are related to organophosphorus pesticides, although they have much higher human acute toxicity than commonly used pesticides. After the detection of the presence of NAs, the critical step is the fast decontamination of the environment in order to avoid the lethal effect of these organophosphorus compounds on exposed humans. This review collects the catalytic degradation reactions of NAs, in particular focusing our attention on chemical hydrolysis. These reactions are catalyzed by different catalyst categories (metal-based, polymeric, heterogeneous, enzymatic and MOFs), all of them described in this review.

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Synthesis and Biological Activity of Novel Diphenyl N- Substituted Carbamimidoylphosphoramidate Derivatives

Cited by 11 publications

References 17 publications

Ultrasound-promoted solvent-free synthesis of some new α-aminophosphonates as potential antioxidants

Ultrasound-promoted solvent-free synthesis of some new α-aminophosphonates as potential antioxidants

Supramolecular Sensing of Chemical Warfare Agents

Catalytic Degradation of Nerve Agents

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