Synthesis and biological response of casein-based silica nano-composite film for drug delivery system

Ma, Jianzhong; Xu, Qunna; Zhou, Jianhua; Zhang, Jing; Zhang, Limin; Tang, Huiru

doi:10.1016/j.colsurfb.2013.06.011

Cited by 40 publications

(14 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Silica nano-composite films have been prepared using the same technique as described elsewhere [37,38,39] with chemicals from Sigma-Aldrich (St. Louis, MO, USA): 1-poly methyl methacrylate (PMMA), 2-methyl ethyketone (MEK), 3-Celite, 4-methanol, 5-polystyrene, 6-poly-4-vinylpyridine (P4VP), 7-polyimide PI derived from pyromellitic dianhydride/oxidianiline PMDA/ODA. The obtained colloidal silica particles have radius about 15 nm with dispersion into the polystyrene and polyimide host matrices.…”

Section: Methodsmentioning

confidence: 99%

Effect of Addition of Colloidal Silica to Films of Polyimide, Polyvinylpyridine, Polystyrene, and Polymethylmethacrylate Nano-Composites

et al. 2016

View full text Add to dashboard Cite

Nano-composite films have been the subject of extensive work for developing the energy-storage efficiency of electrostatic capacitors. Factors such as polymer purity, nanoparticle size, and film morphology drastically affect the electrostatic efficiency of the dielectric material that forms the insulating film between the conductive electrodes of a capacitor. This in turn affects the energy storage performance of the capacitor. In the present work, we have studied the dielectric properties of four highly pure amorphous polymer films: polymethyl methacrylate (PMMA), polystyrene, polyimide and poly-4-vinylpyridine. Comparison between the dielectric properties of these polymers has revealed that the higher breakdown performance is a character of polyimide (PI) and PMMA. Also, our experimental data shows that adding colloidal silica to PMMA and PI leads to a net decrease in the dielectric properties compared to the pure polymer.

show abstract

Section: Methodsmentioning

confidence: 99%

Effect of Addition of Colloidal Silica to Films of Polyimide, Polyvinylpyridine, Polystyrene, and Polymethylmethacrylate Nano-Composites

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Recently, casein and its derivates due to their good biocompatibility, high degradability, and unique film-forming property have attracted more and more attention in substantial fields, such as pharmaceutical, leather finishing, paper making and food packaging [1][2][3][4][5]. However, the major issues prohibiting their widespread use are their poor flexibility, low water repellency and weak environment resistance.…”

Section: Introductionmentioning

confidence: 99%

Facile synthesis of casein-based TiO 2 nanocomposite for self-cleaning and high covering coatings: Insights from TiO 2 dosage

Fan

et al. 2016

Progress in Organic Coatings

Self Cite

View full text Add to dashboard Cite

“…The use of bio-based polymers to prepare pharmaceuticals and biomedical agents has generated considerable research interest in recent years regarding relieving the overdependence on synthetic polymeric materials [1][2][3][4]. In addition, recent advances in the design of polymer-based stimuli-responsive systems have created opportunities for novel applications in different fields such as smart coating [5], biosensors [6] optical materials [7,8] and drug delivery [9], among others.…”

Section: Introductionmentioning

confidence: 99%

“…In view of this, acrylic/casein hybrid materials appear as an excellent alternative due to their improved mechanical properties [21][22][23]. For instance, Ma et al [2] reported the synthesis of casein-based silica nanocomposite films as a drug carrier. These films were found to be pH-responsive, and the silica content was proved to have positive effects on both the drug-loading capacity and drug-releasing behavior.…”

Section: Introductionmentioning

confidence: 99%

pH-responsive casein-based films and their application as functional coatings in solid dosage formulations

Picchio

Paredes

Palma

et al. 2018

Colloids and Surfaces A: Physicochemical and Engineering Aspect

View full text Add to dashboard Cite

Over the past few years, there has been increasing attention to the design of new drug delivery systems based on milk proteins due to their excellent functional properties. In this study, we report a new approach for preparing protein-based coating films using highly methacrylated casein as a macro-crosslinker. The films exhibited a smooth surface and an even casein distribution as evidenced by both scanning electron and atomic force microscopy, respectively. The mechanical behavior of the casein-based films could be easily tuned by controlling the degree of methacrylation of the bio-based crosslinker. The as-prepared films showed pH-dependent swelling, in which the swelling ability in alkaline medium was stronger than that at acid pH. The mechanical, swelling,

show abstract

Synthesis and biological response of casein-based silica nano-composite film for drug delivery system

Cited by 40 publications

References 29 publications

Effect of Addition of Colloidal Silica to Films of Polyimide, Polyvinylpyridine, Polystyrene, and Polymethylmethacrylate Nano-Composites

Effect of Addition of Colloidal Silica to Films of Polyimide, Polyvinylpyridine, Polystyrene, and Polymethylmethacrylate Nano-Composites

Facile synthesis of casein-based TiO 2 nanocomposite for self-cleaning and high covering coatings: Insights from TiO 2 dosage

pH-responsive casein-based films and their application as functional coatings in solid dosage formulations

Contact Info

Product

Resources

About