Synthesis and characterization of bioactive zinc(II) and cadmium(II) complexes with new Schiff bases derived from 4-nitrobenzaldehyde and acetophenone with ethylenediamine

Prakash, Anant; Singh, Brajesh Kumar; Bhojak, N.; Adhikari, Devjani

doi:10.1016/j.saa.2010.03.019

Cited by 79 publications

(37 citation statements)

References 24 publications

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“…The IR spectra of all the metal(II) complexes exhibited major changes in comparison to the spectra of the subsequent ligands. The most prominent change observed was, the carbonyl (C¼O) and thiocarbonyl (C¼S) bands originally appearing at 1675-1680 and 1235-1250 cm À1 in the spectra of the ligand, shifted to lower frequency by 13-15 cm À1 at 1660-1670 and 1220-1237 cm À1 , respectively, in the spectra of metal(II) complexes indicating 1,26 the involvement in coordination with the metal(II) ions. The decrease in frequency is due to delocalization of electrons …”

Section: Chemistrymentioning

confidence: 98%

Metal based drugs: design, synthesis and in-vitro antimicrobial screening of Co(II), Ni(II), Cu(II) and Zn(II) complexes with some new carboxamide derived compounds: crystal structures of N-[ethyl(propan-2-yl)carbamothioyl]thiophene-2-carboxamide and its copper(II) complex

Sumrra

Hanif

Chohan

et al. 2015

Journal of Enzyme Inhibition and Medicinal Chemistry

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Section: Chemistrymentioning

confidence: 98%

Metal based drugs: design, synthesis and in-vitro antimicrobial screening of Co(II), Ni(II), Cu(II) and Zn(II) complexes with some new carboxamide derived compounds: crystal structures of N-[ethyl(propan-2-yl)carbamothioyl]thiophene-2-carboxamide and its copper(II) complex

Sumrra

Hanif

Chohan

et al. 2015

Journal of Enzyme Inhibition and Medicinal Chemistry

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“…Mass spectrum of the hydrazone was recorded using QP 2010 model Shimadzu GCMS. 1 Hnmr and 13 Cnmr spectral studies were carried out on Bruker Avance III HD.…”

Section: Methodsmentioning

confidence: 99%

“…1 Hnmr spectrum displayed nine signals for nine distinguished hydrogen atoms. The signal appeared at 2.28  was due to the methyl protons (Table 1).…”

Section: Characterization Of Phenylhydrazonementioning

confidence: 99%

“…A weak but broad signal appeared at 9.86  was assignable to the NH proton of phenylhydrazine part. Two dimensional 1 H- 1 Hnmr spectrum (COSY) was very helpful in identifying different hydrogen atoms (Figure 1). Nine diagonal contours were appeared in the COSY spectrum, for nine different protons of the molecule.…”

Section: Characterization Of Phenylhydrazonementioning

confidence: 99%

“…Such molecules and their metal chelates are having wide variety of applications in the pharmaceutical, catalysis, analytical and corrosion field [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] . In the present investigation we explored the structure of the 3-acetylpyridine phenylhydrazone and its copper chelate using various spectroscopic methods.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Chelating Competency and Electrochemical Response of a Heterocyclic Phenylhydrazone and its Copper Chelate

Raphael¹,

Kakkassery²,

Shaju³

et al. 2014

Orient J Chem

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Heterocyclic compound 3-acetylpyridine phenylhydrazone (APPH) and its copper chelate were synthesized and characterized by spectral, elemental, magnetic and conductance measurements. Investigations showed that APPH behaved as bidentate ligand during chelation. The square planar geometry of the chelate was confirmed by magnetic and optical spectral studies. The detailed electrochemical response of the ligand and chelate were evaluated and reported.

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Synthesis, spectral characterization and biological studies of transition metal(II) complexes with triazole Schiff bases

Hanif

Chohan

2012

Applied Organom Chemis

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New metal based triazoles (1-12) have been synthesized by the interaction of novel Schiff base ligands (L 1 -L 3 ) with the Co(II), Ni(II), Cu(II) and Zn(II) metal ions. The Schiff base ligands and their all metal(II) complexes have been thoroughly characterized using various physical, analytical and spectroscopic techniques. In vitro bacterial and fungal inhibition studies were carried out to examine the antibacterial and antifungal profile of the Schiff bases in comparison to their metal(II) complexes against two Gram-positive, four Gram-negative and six fungal strains. The bioactivity data showed the metal(II) complexes to have more potent antibacterial and antifungal activity than their uncomplexed parent Schiff bases against one or more bacterial and fungal species. R Scheme 1. Preparation of the Schiff base ligands (L 1 -L 3 ). Scheme 2. Proposed structure of the metal(II) complexes (1-12).Synthesis, triazole Schiff bases, metal complexes, biological activity Average of ligands (L 1 -L 3 ) = 13.47 mm; average of complexes (1-12) = 17.24 mm.

show abstract

Synthesis and characterization of bioactive zinc(II) and cadmium(II) complexes with new Schiff bases derived from 4-nitrobenzaldehyde and acetophenone with ethylenediamine

Cited by 79 publications

References 24 publications

Metal based drugs: design, synthesis and in-vitro antimicrobial screening of Co(II), Ni(II), Cu(II) and Zn(II) complexes with some new carboxamide derived compounds: crystal structures of N-[ethyl(propan-2-yl)carbamothioyl]thiophene-2-carboxamide and its copper(II) complex

Metal based drugs: design, synthesis and in-vitro antimicrobial screening of Co(II), Ni(II), Cu(II) and Zn(II) complexes with some new carboxamide derived compounds: crystal structures of N-[ethyl(propan-2-yl)carbamothioyl]thiophene-2-carboxamide and its copper(II) complex

Chelating Competency and Electrochemical Response of a Heterocyclic Phenylhydrazone and its Copper Chelate

Synthesis, spectral characterization and biological studies of transition metal(II) complexes with triazole Schiff bases

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