Synthesis and Characterization of β-Diketimine Schiff Base Complexes with Ni(II) and Zn(II) Ions: Experimental and Theoretical Study

Abstract

Schiff base diethyl 4,4-(pentane-2,4-diylidenebis(azanylylidene))benzoate (1) as a new ligand (L) was prepared by the reaction of acetylacetone with benzocaine in the ratio of 1 : 1. Two transition-metal complexes, [Ni(II)(LCl(HOEt))] (2) and [Zn(II)(LCl(HOEt))] (3), have been synthesized from metal salts with didentate Schiff base ligand (L) and characterized by elemental analyses, FT-IR, 1 H NMR, 13 C NMR UV-Vis spectroscopy, and magnetic susceptibility. e biological activity of the complexes was studied. In addition, the M06-2x density function theory method and the 6-31G(d) basic set were applied to determine the optimized structures of 1-3 and to determine their IR and 1 H NMR, 13 C NMR spectra theoretically. e data are in good agreement with the experimental results. e geometries of complexes 2 and 3 were determined to be square-planar for 2 and tetrahedral for 3.

Synthesis and Evaluation of Cytotoxicity Effect of New Ligand (LBe) and it's Complexes on a Cervical Cancer

“…The Zinc complex showed no absorption band for (d-d) transition because the d orbital is field. The spectra of Zn complex, show change in the bands position compared to that of the free ligand due to charge transfer between Zn(II) and ligand, that is a good result for zinc(II) tetrahedral complex 36,37 . Table 2 explain UV-Vis bands of the ligand and all complexes with their assigned transition.…”