Synthesis and characterization of new water stable antimony(III) complex with pyrimidine-2-thione and in vitro biological study

Synthesis, structural characterization and biological study of new organotin(IV), silver(I) and antimony(III) complexes with thioamides

“…The complexes isolated during our studies exhibit octahedral cationic structures, structures (Scheme 9; 21,22), square pyramidal (SP) geometry with cis-S, cis-Cl conformations (Scheme 9; 23 and 25) or trans-S, trans-Cl (Scheme 9; 24) [25,26]. XRPD diagram measured of 21, before and after heating at 150°C for 12 h (A, B) and the calculated XRPD diagram of 23 from its XRD pattern show a geometry transformation in solid state, from octahedral to square pyramidal conformation upon heating and dehydration.…”

“…We have thus, prepared Sb ( [25,26]. The molecular structures of these Sb(III) complexes are given in Scheme 9 [25,26].…”

“…With the aim to synthesize new antitumor agents based on organotin(IV), silver(I) or antimony(III) compounds we studied the interaction of R 3 SnCl and R 2 SnCl 2 (R = phenyl-, n-butyl-, methyl-) [17][18][19][20][21], AgX (X = NO 3 , Cl, Br, I) [22][23][24] or SbCl 3 [25,26] with the thioamides 5-chloro-2-mercapto-benzothiazole (CMBZT), 2-mercaptobenzothiazole (MBZT), 2-mercapto-thiazoline (MTZD), 2-mercapto-benzoxazole (MBZO), 2-mercapto-benzimidazole (MBZIM), 5-ethoxy-2-mercapto-benzimidazole (EMBZ-IM), 2-mercapto-pyrimidine (PMTH), 2-mercapto-3,4,5,6-tetrahydro-pyrimidine (STPMH 2 ), 2-mercapto-nicotinic acid (H 2 MNA). In case of silver(I) complexes tri(p-toly)-phosphine (TPTP) was, also, used as ligand [27].…”

Anticancer Activity of Molecular Compounds of Arsenic, Antimony and Bismuth

“…In probably the most sustained systematic study of antiproliferative activities of antimony compounds, their complexation with various heterocyclic thioamides was researched, with the latter being present in the neutral and/or deprotonated forms [60][61][62][63]. As a consequence, a full range of coordination geometries and aggregation patterns have been determined for these derivatives.…”

Synthesis and Characterization of Antimony(III) Complexes of Thioamides, and Crystal Structure of {[Sb(Imt)2Cl2]2((2‐Imt)}Cl2(Imt=Imidazolidine‐2‐thione)

“…[17][18][19] Structural studies on antimony(III) complexes of thioamides have shown that antimony(III) is quite variable in the geometries of its sulfur coordination which can vary between square pyramidal, trigonal bipyramidal and octahedral. [4][5][6][7][8][20][21][22][23][24] The structures are usually distorted because the lone pair of electrons on antimony atom affects the ideal geometry as expected from Valence Shell Electron Pair Repulsion Theory. [4][5][6] These studies further demonstrate that thiones can act both as terminal or bridging ligands [4][5][6][7][8][9][21][22][23][24] leading to the formation of polymeric structures, such as [SbBr 3 (µ 2 -Diaz)(Diaz)] n (Diaz ＝ Diazinane-2-thione).…”