Synthesis and characterization of poly[N-isopropylacrylamide-co-1-(N,N-bis-carboxymethyl)amino-3-allylglycerol] grafted to magnetic nano-particles for the extraction and determination of fluvoxamine in biological and pharmaceutical samples

Panahi, Homayon Ahmad; Tavanaei, Yasamin; Moniri, Elham; Keshmirizadeh, Elham

doi:10.1016/j.chroma.2014.04.031

Cited by 27 publications

(14 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although in situ local tumors can be successfully removed by magnetic nanoparticles, they may induce human normal cells to produce immune rejection and easily penetrate and escape from the tumor tissue due to their exogenous 26,27 . Therefore, the ideal magnetic nanoparticles should have immune escape and tumor accumulation abilities for the purpose of treating tumors.…”

Section: Introductionmentioning

confidence: 99%

Cancer cell membrane-coated mesoporous silica loaded with superparamagnetic ferroferric oxide and Paclitaxel for the combination of Chemo/Magnetocaloric therapy on MDA-MB-231 cells

Cai

Liu

Han

et al. 2019

Sci Rep

View full text Add to dashboard Cite

To effectively inhibit the growth of breast cancer cells (MDA-MB-231 cells) by the combination method of chemotherapy and magnetic hyperthermia, we fabricated a biomimetic drug delivery (CSiFePNs) system composed of mesoporous silica nanoparticles (MSNs) containing superparamagnetic ferroferric oxide and Paclitaxel (PTX) coated with MDA-MB-231 cell membranes (CMs). In the in vitro cytotoxicity tests, the MDA-MB-231 cells incubated with CSiFePNs obtained IC50 value of 0.8 μgL−1, 3.5-fold higher than that of SiFePNs. The combination method of chemotherapy and magnetic hyperthermia can effectively inhibit the growth of MDA-MB-231 cells.

show abstract

Section: Introductionmentioning

confidence: 99%

Cancer cell membrane-coated mesoporous silica loaded with superparamagnetic ferroferric oxide and Paclitaxel for the combination of Chemo/Magnetocaloric therapy on MDA-MB-231 cells

Cai

Liu

Han

et al. 2019

Sci Rep

View full text Add to dashboard Cite

show abstract

“…This paper showed that the modification of the Fe 3 O 4 nanoparticle with two relatively harmless biocompatible polymers of polyvinyl alcohol and methylcellulose is effective in enhancing the loading and controlled release of Enalapril. Polymers created more active sites at the surface for entrapment of the drug by increasing the surface area and the formation of a polymer network. SEM, FTIR spectra, TGA and CHN elemental analysis, confirmed the formation of the polymer network on the surface of nanoparticles.…”

Section: Discussionmentioning

confidence: 99%

Synthesis and Evaluation of Enalapril‐Loaded PVA/PMC Modified Magnetic Nanoparticles as a Novel Efficient Nano‐Carrier

2019

Self Cite

View full text Add to dashboard Cite

In the present study, the development of new Enalapril‐loaded adsorbent and evaluation of drug release was studied in vitro. Initially, Fe3O4 magnetic nanoparticles were synthesized via co‐precipitation method. Then, the mixture of polymers was deposited on the surface of the magnetic nanoparticles via radical polymerization in order to enhance the adsorption capacity of nanoparticles with biocompatible poly methylcellulose modified with polyvinyl alcohol. The equilibrium adsorption data magnetite nano‐sorbent were analyzed using Langmuir, Freundlich, and Temkin. The drug‐release study showed that 80% of Enalapril released in the simulated gastrointestinal environment for 18 hours. The samples and products analyzed by FTIR, elemental analysis, thermal gravimetric analysis (TGA) and scanning electron microscopy (SEM). Adsorption parameters such as pH, temperature and contact time were optimized, and Langmuir, Freundlich and Temkin's isotherms were studied for the drug adsorption mechanism. The release process of Enalapril studied in the simulated human digestive environment. The release profile of Enalapril has a very steep slope for 30 minutes in the simulated human gastric.

show abstract

“…The synthesis of magnetic nanoparticles was accomplished according to the method given in the literature . The cheapest, simplest, and most environmentally friendly method is based on the coprecipitation, which involves the addition of ammonium hydroxide solution into an aqueous solution of Fe 2+ and Fe 3+ salts under conditions of a nitrogen atmosphere and vigorous stirring.…”

Section: Methodsmentioning

confidence: 99%

Functionalized superparamagnetic nanoparticles with a polymer containing β‐cyclodextrin for the extraction of sertraline hydrochloride in biological samples

Shamekhi

Alaei

2017

J of Separation Science

Self Cite

View full text Add to dashboard Cite

In this study, a novel magnetic nanoadsorbent was synthesized by grafting β-cyclodextrin onto the modified surface of Fe O nanoparticles for the sorption and extraction of sertraline hydrochloride from human biological fluids. The extracted sertraline hydrochloride was measured by high-performance liquid chromatography. The grafted nanosorbent was confirmed by Fourier transform infrared spectroscopy, transmission electron microscopy, thermogravimetric analysis, and elemental analysis. The kinetic sorption of sertraline hydrochloride by magnetic nanosorbent was 1 h. The best temperature for sorption of sertraline hydrochloride was at 25°C at an optimum pH of 5. The adsorbed sertraline hydrochloride can be desorbed by using methanol solution containing acetic acid (5%) and trifluoroacetic acid (1%).

show abstract

Synthesis and characterization of poly[N-isopropylacrylamide-co-1-(N,N-bis-carboxymethyl)amino-3-allylglycerol] grafted to magnetic nano-particles for the extraction and determination of fluvoxamine in biological and pharmaceutical samples

Cited by 27 publications

References 39 publications

Cancer cell membrane-coated mesoporous silica loaded with superparamagnetic ferroferric oxide and Paclitaxel for the combination of Chemo/Magnetocaloric therapy on MDA-MB-231 cells

Cancer cell membrane-coated mesoporous silica loaded with superparamagnetic ferroferric oxide and Paclitaxel for the combination of Chemo/Magnetocaloric therapy on MDA-MB-231 cells

Synthesis and Evaluation of Enalapril‐Loaded PVA/PMC Modified Magnetic Nanoparticles as a Novel Efficient Nano‐Carrier

Functionalized superparamagnetic nanoparticles with a polymer containing β‐cyclodextrin for the extraction of sertraline hydrochloride in biological samples

Contact Info

Product

Resources

About